| .VPL | Unknown Developer | Gegevensbestanden | Karaoke Player Playlist | vanBasco's Karaoke Player | Open Source |
| .VPN | Qbik | Gegevensbestanden | WinGate VPN Configuration | WinGate VPN | Qbik |
| .VPP | Visual Paradigm | Gegevensbestanden | Visual Paradigm Project File | Visual Paradigm Suite | Visual Paradigm |
| .VPR | Adobe Systems Incorporated | Gegevensbestanden | Adobe Premiere Preset | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .VPS | H+H Software GmbH | Gegevensbestanden | Virtual CD Copy Template | H+H Software Virtual CD | H+H Software GmbH |
| .VPU | Avast Software | Gegevensbestanden | Avast! Antivirus Data File | Avast Antivirus | Avast Software |
| .VPX | Avast Software | Gegevensbestanden | Avast! Virus Update File | Avast Antivirus | Avast Software |
| .VRD | Microsoft Corporation | Gegevensbestanden | Visio Report Definition File | Microsoft Visio | Microsoft Corporation |
| .VRM | Augmentra Ltd | Gegevensbestanden | ViewRanger Map File | ViewRanger | Augmentra Ltd |
| .VRT | Superscape | Gegevensbestanden | Virtual World | Internet Explorer | Microsoft Corporation |
| .VRX | Microsoft Corporation | Gegevensbestanden | Report Data File | Microsoft Project 2016 | Microsoft Corporation |
| .VS | OpenGL | Gegevensbestanden | Vertex Shader File | Microsoft DirectX SDK | Microsoft Corporation |
| .VSG | Anritsu | Gegevensbestanden | Anritsu Vector Signal Generator Data | Vector Signal Generator | Anritsu |
| .VSGLOG | Microsoft Corporation | Gegevensbestanden | Visual Studio File | Microsoft Visual Studio | Microsoft Corporation |
| .VSHADER | Microsoft Corporation | Gegevensbestanden | Microsoft Visual Studio Data File | Microsoft Visual Studio | Microsoft Corporation |
| .VSMDI | Microsoft Corporation | Gegevensbestanden | Microsoft Visual Studio Test Metadata | Microsoft Visual Studio | Microsoft Corporation |
| .VSPF | Microsoft Corporation | Gegevensbestanden | Microsoft Visual Studio Performance Rules File | Microsoft Visual Studio | Microsoft Corporation |
| .VSR | Microsoft Corporation | Gegevensbestanden | Microsoft Access Report | Microsoft Access | Microsoft Corporation |
| .VSS | The Omni Group | Gegevensbestanden | Visio Stencil File | Microsoft Word 2016 | Microsoft Corporation |
| .VSSM | Microsoft Corporation | Gegevensbestanden | Microsoft Visio 2013 Macro-Enabled Stencil File | Microsoft Office | Microsoft Corporation |
| .VSSX | Microsoft Corporation | Gegevensbestanden | Microsoft Visio Stencil Data | Microsoft Office | Microsoft Corporation |
| .VST | Microsoft Corporation | Gegevensbestanden | Targa Bitmap Image File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .VSTO | Microsoft Corporation | Gegevensbestanden | Microsoft Visual Studio Data | Microsoft Visual Studio | Microsoft Corporation |
| .VSV | Microsoft Corporation | Gegevensbestanden | Virtual Machine Saved State File | Windows Virtual PC | Microsoft Corporation |
| .VSX | Microsoft Corporation | Gegevensbestanden | Visio Stencil XML File | Microsoft Visio | Microsoft Corporation |
| .VT | Unknown Developer | Gegevensbestanden | VT100 Terminal Data File | Unknown Software | Unknown Developer |
| .VTC | HBM PRENSCIA INC. | Gegevensbestanden | BrainVoyager QX Time Course Data | ReliaSoft ALTA | HBM PRENSCIA INC. |
| .VTD | Microsoft Corporation | Gegevensbestanden | Microsoft VOLT Glyph Data | Microsoft Windows | Microsoft Corporation |
| .VTI | Kitware, Inc. | Gegevensbestanden | Visualization Toolkit Image Data | Visualization ToolKit | Interscape |
| .VTL | Paul Rädle | Gegevensbestanden | Vocabulary Trainer File | Vocabulary Trainer (VTrain) | Paul Rädle |
| .VTP | Kitware, Inc. | Gegevensbestanden | Visualization Toolkit Polygonal Data | Visualization ToolKit | Interscape |
| .VTS | Intel Corporation | Gegevensbestanden | Intel VTune Program Performance Monitor Project | Intel VTune | Intel Corporation |
| .VTX | Richard Bannister | Gegevensbestanden | VTX Chiptune File | Audio Overload | Richard Bannister |
| .VU | Sony | Gegevensbestanden | Playstation 2 VU Development Source Code | PlayStation 2 | Sony |
| .VUD | Microsoft Corporation | Gegevensbestanden | Virtual Machine Undo Drive File | Windows Virtual PC | Microsoft Corporation |
| .VUE | E-on Software, Inc. | Gegevensbestanden | Vue Scene File | E-on Vue | E-on Software, Inc. |
| .VVF | Open Source | Gegevensbestanden | Voc Vocabulary File | Voc | Open Source |
| .VVR | Unknown Developer | Gegevensbestanden | ViVerify Repair File | ViVerify Repair | Unknown Developer |
| .VWR | The Wireshark Team | Gegevensbestanden | Ixia IxVeriWave RAW 802.11 Capture File | Wireshark | The Wireshark Team |
| .VWS | SmartWare Corporation | Gegevensbestanden | SmartWare Standard View | SmartWare | SmartWare Corporation |
| .VXF | Microsoft Corporation | Gegevensbestanden | Microsoft Money Data | Microsoft Money | Microsoft Corporation |
| .VXM | Vista Software | Gegevensbestanden | vTask Studio File | vTask Studio | Vista Software |
| .VXML | Voxeo Corporation | Gegevensbestanden | VoiceXML File | Microsoft Notepad | Microsoft Corporation |
| .VXP | Interscape | Gegevensbestanden | Mobile Application File | Mediatek MRE SDK | MediaTek |
| .VYM | SourceForge | Gegevensbestanden | VYM Mind Map File | VYM | SourceForge |
| .VZM | Verizon | Gegevensbestanden | Verizon Message File | Message+ | Verizon |
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