| .Q | Open Source | Gegevensbestanden | Tinn-R Editor Data | Tinn-R Editor | Open Source |
| .Q00 | Intuit, Inc. | Gegevensbestanden | Quicken 2000 Tax Return | Intuit Quicken | Quicken |
| .Q07 | Intuit, Inc. | Gegevensbestanden | QuickTax 2007 Tax Return Data | Quicktax Suite | Intuit, Inc. |
| .Q08 | Intuit, Inc. | Gegevensbestanden | QuickTax 2008 Tax Return | Quicktax Suite | Intuit, Inc. |
| .Q3D | Act-3D | Gegevensbestanden | Quest3D Project File | Quest3D | Act-3D |
| .Q43 | Unknown Developer | Gegevensbestanden | Aqbanking Q43 File Format | AqBanking | Open Source |
| .Q4W | Nutek, Inc. | Gegevensbestanden | Qualitek-4 Exported Data | Qualitek-4 | Nutek, Inc. |
| .Q99 | Quicken | Gegevensbestanden | Quicken 99 File | Intuit Quicken | Quicken |
| .QAF | Image Intelligence Software | Gegevensbestanden | Qedoc Quiz Player Autolaunch Data | Qedoc Quiz Player | Image Intelligence Software |
| .QB | Blackboard Collaborate | Gegevensbestanden | Diploma Question Bank File | Wimba Diploma | Blackboard Collaborate |
| .QB1 | Quicken | Gegevensbestanden | Quicken Data | Intuit Quicken | Quicken |
| .QB2013 | Intuit, Inc. | Gegevensbestanden | QuickBooks 2013 File | Intuit QuickBooks for Mac | Intuit, Inc. |
| .QBA | Intuit, Inc. | Gegevensbestanden | QuickBooks Accountant's Copy Work File | Intuit QuickBooks Pro | Intuit, Inc. |
| .QBE | Corel | Gegevensbestanden | Corel Quattro Pro Saved Query File | Corel Quattro Pro | Corel |
| .QBJ | Intuit, Inc. | Gegevensbestanden | QuickBooks General Journal Entry File | QuickBooks | Intuit, Inc. |
| .QBL | Broderbund | Gegevensbestanden | Business Lawyer Document Files | Home & Business Lawyer | Broderbund |
| .QBO | Intuit, Inc. | Gegevensbestanden | QuickBooks Online Bank Statement File | FreshBooks | FreshBooks Company |
| .QBR | Intuit, Inc. | Gegevensbestanden | QuickBooks Report Template | QuickReport | QBS Software |
| .QBS | Microsoft Corporation | Gegevensbestanden | Microsoft QuickBasic Program File | QuickBASIC | Microsoft Corporation |
| .QBW | Intuit, Inc. | Gegevensbestanden | QuickBooks Data File | Intuit QuickBooks Pro | Intuit, Inc. |
| .QBXML | Intuit, Inc. | Gegevensbestanden | QuickBooks XML Format File | Zed Axis | Zed Systems |
| .QCA | Sony Mobile Communications | Gegevensbestanden | Ericsson Phone Doubler Quick Call Data | Ericsson Phone Doubler Quick Call | Sony Mobile Communications |
| .QCALL | Sony Mobile Communications | Gegevensbestanden | Phone Doubler Quick Call File | Ericsson Phone Doubler Quick Call | Sony Mobile Communications |
| .QCC | Niobrara R&D Corporation | Gegevensbestanden | NIOBRARA QUCM Firmware File | Unknown Software | Unknown Developer |
| .QCH | Quicken | Gegevensbestanden | Quicken DOS Data File | Intuit Quicken | Quicken |
| .QCK | Esoteric Technologies | Gegevensbestanden | Jigsaw 2 Astrological Tool File | JigSaw | Esoteric Technologies |
| .QCM | Unknown Developer | Gegevensbestanden | Quick Command Data | Unknown Software | Unknown Developer |
| .QD | SourceForge | Gegevensbestanden | SHARP MZ-series Emulator Data | Sharp MZ-800 Emulator | SourceForge |
| .QDAT | Apple | Gegevensbestanden | QuickTime Install Cache File | Apple QuickTime Player | Apple |
| .QDB | Intuit, Inc. | Gegevensbestanden | Quicken 5 & 6 Data File | Intuit Quicken | Quicken |
| .QDF | Ringler Informatik AG | Gegevensbestanden | Snapform File | Snapform Designer | Ringler Informatik AG |
| .QDP | NASA | Gegevensbestanden | Quick And Dandy Plotter File | Quick and Dandy Plotter (QDP) | NASA |
| .QEF | Microsoft Corporation | Gegevensbestanden | Microsoft Excel Query File | Microsoft Excel | Microsoft Corporation |
| .QEL | Intuit, Inc. | Gegevensbestanden | Quicken Electronic Library File | Intuit Quicken | Quicken |
| .QEM | ExpensAble | Gegevensbestanden | ExpensAble Report File | ExpensAble Office | ExpensAble |
| .QES | Askia SAS | Gegevensbestanden | Askiadesign Questionnaire File | Askiadesign | Askia SAS |
| .QEX | ExpensAble | Gegevensbestanden | ExpensAble Data File | ExpensAble Office | ExpensAble |
| .QF | Nokia | Gegevensbestanden | Nokia (Ovi) Maps Version Data | Microsoft Notepad | Microsoft Corporation |
| .QFD | Quicken | Gegevensbestanden | Quicken Data | Intuit Quicken | Quicken |
| .QFL | Nolo | Gegevensbestanden | Family Lawyer Document | Nolo Quicken WillMaker | Nolo |
| .QFX | Intuit, Inc. | Gegevensbestanden | Quicken Financial Exchange File | Intuit Quicken | Quicken |
| .QHF | Ilgam Zyulkorneev | Gegevensbestanden | QIP Saved History File | QIP | Ilgam Zyulkorneev |
| .QID | Quicken | Gegevensbestanden | Quicken File | Intuit Quicken | Quicken |
| .QIF | Intuit, Inc. | Gegevensbestanden | Quicken Interchange Format File | Intuit Quicken | Quicken |
| .QIP | Ilgam Zyulkorneev | Gegevensbestanden | QIP Infium Account File | QIP | Ilgam Zyulkorneev |
| .QL | Robelle | Gegevensbestanden | QEdit Data | QEDIT | Robelle |
| .QLC | Adobe Systems Incorporated | Gegevensbestanden | Adobe PostScript Help File | Adobe Creative Suite | Adobe Systems Incorporated |
| .QLD | Waters Corporation | Gegevensbestanden | MassLynx Quantation Data | MassLynx | Waters Corporation |
| .QLV | QGIS (Quantum GIS) | Gegevensbestanden | QGIS LayerVersion Data | QGIS | QGIS (Quantum GIS) |
| .QM | Digia Oyj | Gegevensbestanden | Qt Compiled Translation Source File | Nokia Qt Linguist | Nokia |
| .QMA | Robelle | Gegevensbestanden | QEDIT Data File | QEDIT | Robelle |
| .QMB | Matthieu Godon | Gegevensbestanden | Quick Menu Builder Saved File | Quick Menu Builder | Matthieu Godon |
| .QMBL | Vernier Software & Technology | Gegevensbestanden | LabQuest Results Data | Vernier Logger Pro | Vernier Software & Technology |
| .QME | Intuit, Inc. | Gegevensbestanden | Quicken Win V3 Data | Intuit Quicken | Quicken |
| .QMO | inData | Gegevensbestanden | TrialDirector Object Load List | TrialDirector | inData |
| .QMR | Steve Sneed | Gegevensbestanden | OzWin Quickscan History File | OzWin | Steve Sneed |
| .QMSB | Questionmark | Gegevensbestanden | Questionmark Secure Data | Secure | Questionmark |
| .QMV | QVOD Technology | Gegevensbestanden | Qvod Player Data | QVOD Player | QVOD Technology |
| .QPB | Intuit, Inc. | Gegevensbestanden | QuickBooks Point Of Sale Data File | QuickBooks Point of Sale | Intuit, Inc. |
| .QPF | Act-3D | Gegevensbestanden | Quest3D Project File | Quest3D | Act-3D |
| .QPH | Digia Oyj | Gegevensbestanden | Qt Phrase Books File | Qt SDK | The Qt Company |
| .QPK | Unknown Developer | Gegevensbestanden | Qt Extended Installable Package | Qt Extended | Open Source |
| .QPL | Synergy Software | Gegevensbestanden | KaleidaGraph Layout File | KaleidaGraph | Synergy Software |
| .QPP | BenQ | Gegevensbestanden | QPresenter Pro Presentation | QPresenter Pro | BenQ |
| .QPS | Open Source | Gegevensbestanden | CUTEr QPS Model | CUTEr | Open Source |
| .QR2 | Embarcadero Technologies | Gegevensbestanden | Delphi Database Quick Report | Delphi (IDE) | Embarcadero Technologies |
| .QRC | Quark Software Inc. | Gegevensbestanden | QuarkXPress Required Component File | QuarkXPress | Quark Software Inc. |
| .QRD | Hummingbird Ltd. | Gegevensbestanden | BI/Query Result Data | BI Query Chart Editor | Hummingbird Ltd. |
| .QRL | Quality First Software | Gegevensbestanden | QF-Test Run Log | QF-Test | Quality First Software |
| .QRP | QBS Software | Gegevensbestanden | QuickReport Report File | QuickReport | QBS Software |
| .QRS | Corel Corporation | Gegevensbestanden | Corel WordPerfect Equation Editor Support Data | Corel WordPerfect X8 | Corel |
| .QSB | Lenovo | Gegevensbestanden | Lenovo Firmware Update | Unknown Software | Unknown Developer |
| .QSD | Quicken | Gegevensbestanden | Quicken Data | Intuit Quicken | Quicken |
| .QSF | Qualtrics | Gegevensbestanden | Qualtrics Survey File | Qualtrics Survey Solutions (online) | Qualtrics |
| .QSN | Howard Benner | Gegevensbestanden | TapCIS QuickScan Data | TAPCIS | Howard Benner |
| .QST | Synergy Software | Gegevensbestanden | KaleidaGraph Style File | KaleidaGraph | Synergy Software |
| .QT1 | Payroll Associates, LLC | Gegevensbestanden | ViewChoice File | ViewChoice | Payroll Associates, LLC |
| .QTB | Turning Technologies | Gegevensbestanden | ExamView QuickTake Question Bank Data | ExamView | Turning Technologies |
| .QTN | Norman | Gegevensbestanden | Norman Virus Control | AVG Internet Security | AVG Technologies |
| .QTPP | Ronald E. Mercer | Gegevensbestanden | Qtracker Update Data | Qtracker | Ronald E. Mercer |
| .QTV | Apple | Gegevensbestanden | QuickTime Virtual Reality File | Apple QuickTime Player | Apple |
| .QUB | KPMG | Gegevensbestanden | Qubus | Qubus | KPMG |
| .QUE | GlobalSCAPE | Gegevensbestanden | CuteFTP Queue Data | CuteFTP | GlobalSCAPE |
| .QUEST | Unknown Developer | Gegevensbestanden | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Atom | GitHub, Inc. |
| .QUICKDRAW | Unknown Developer | Gegevensbestanden | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Atom | GitHub, Inc. |
| .QUT | IBM | Gegevensbestanden | IBM Voice Type Languages Vocable File | IBM Voice Type | IBM |
| .QVP | Qarbon | Gegevensbestanden | Qarbon ViewletBuilder Project File | ViewletBuilder | Qarbon |
| .QVW | Qlik | Gegevensbestanden | QlikView Document | QlikTech International QlikView | Qlik |
| .QW5 | Intuit, Inc. | Gegevensbestanden | Quicken Win Version 5 File | Intuit Quicken | Quicken |
| .QWB | Microsoft Corporation | Gegevensbestanden | Microsoft Money Data | Microsoft Money | Microsoft Corporation |
| .QWP | Sam Bellotto Jr. | Gegevensbestanden | Quiptics Puzzle Data | Quiptics | Sam Bellotto Jr. |
| .QWZ | Question Writer Corporation | Gegevensbestanden | Question Writer File | Question Writer | Question Writer Corporation |
| .QXF | Quicken | Gegevensbestanden | Quicken Essentials For Mac Exchange | Intuit Quicken | Quicken |
| .QXL | Quark Software Inc. | Gegevensbestanden | QuarkXPress Library | QuarkXPress | Quark Software Inc. |
| .QZ | PC Shareware, Inc. | Gegevensbestanden | Create A Quiz Data File | Create A Quiz | PC Shareware, Inc. |
| .QZS | Luzius Schneider | Gegevensbestanden | QuizPro Data File | QuizPro | Luzius Schneider |
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