| .XCH | Link-Assistant.com | Gegevensbestanden | LinkAssistant Project | LinkAssistant | Link-Assistant.com |
| .XCK | Unknown Developer | Gegevensbestanden | Extended Crack File | Unknown Software | Unknown Developer |
| .XCN | Broad Institute | Gegevensbestanden | GenePattern XCN Data File | GenePattern | Broad Institute |
| .XCO | Xilinx, Inc. | Gegevensbestanden | Xilinx CORE Generator Log | Xilinx CORE Generator System | Xilinx, Inc. |
| .XD | Unknown Developer | Gegevensbestanden | CCS-lib.2 Examples Motif-CC File | Unknown Software | Unknown Developer |
| .XDB | Symantec Corporation | Gegevensbestanden | Symantec Virus Database File | Symantec EndPoint Protection 12 | Symantec Corporation |
| .XDF | NASA | Gegevensbestanden | Extended Disk Format Image | OS/2 | IBM |
| .XDP | Adobe Systems Incorporated | Gegevensbestanden | XML Data Package | Adobe Acrobat DC | Adobe Systems Incorporated |
| .XDR_TOR | Accelrys Software Inc. | Gegevensbestanden | Insight II Binary Torsion File | Insight II | Accelrys Software Inc. |
| .XDS | Nintendo | Gegevensbestanden | DS Game Maker Project File | Invisionsoft DS Game Maker | Nintendo |
| .XDT | Olivier F5MZN | Gegevensbestanden | Win-Test Extra Data | Win-Test | Olivier F5MZN |
| .XED | Unknown Developer | Gegevensbestanden | XED Chemical Modeler Input/Output Data | Unknown Software | Unknown Developer |
| .XEF | X-Genics Limited | Gegevensbestanden | eManager Form Data | X-Genics eManager | X-Genics Limited |
| .XEM | X-Genics Limited | Gegevensbestanden | eManager Metered Units | X-Genics eManager | X-Genics Limited |
| .XEN | Activision | Gegevensbestanden | Guitar Hero 3 Data File | Guitar Hero 3 | Neversoft |
| .XER | Oracle Corporation | Gegevensbestanden | Primavera Project Management Proprietary Exchange Format | Primavera | Oracle Corporation |
| .XFC | Blacksun Software | Gegevensbestanden | X-Fonter Font Collection | X-Fonter | Blacksun Software |
| .XFD | JetForm | Gegevensbestanden | FormFlow 99 Form Data File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .XFDF | Adobe Systems Incorporated | Gegevensbestanden | Adobe Acrobat XFDF File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .XFI | Leslie Lamport | Gegevensbestanden | Latex Figures File | LaTex | Leslie Lamport |
| .XFO | Syncro Soft | Gegevensbestanden | XSL-FO Formatted Form | Software602 602XML Form Filler | Software602 |
| .XFR | TIBCO Software Inc | Gegevensbestanden | iProcess Process Definition File | TIBCO iProcess Suite | Xmarter |
| .XFT | Cay Horstmann | Gegevensbestanden | ChiWriter Printer Font | ChiWriter | Cay Horstmann |
| .XG0 | Corel Corporation | Gegevensbestanden | Corel Paradox Secondary Index | Corel WordPerfect X8 | Corel |
| .XG1 | Corel Corporation | Gegevensbestanden | Corel Paradox Secondary Index | Corel WordPerfect X8 | Corel |
| .XG5 | Corel | Gegevensbestanden | Corel Paradox Secondary Index Data File | Corel Paradox | Corel |
| .XGM | Metaphoric Software | Gegevensbestanden | Techno Toys XG-909 MIDI Drum Machine File | XG-909 | Metaphoric Software |
| .XGO | GeoConcept SA | Gegevensbestanden | GeoConcept Add-on | GeoConcept | GeoConcept SA |
| .XGP | Open Source | Gegevensbestanden | Xfire Game Patcher File | XGP | Open Source |
| .XIP | Apple | Gegevensbestanden | MacOS Signed Archive | Apple Archive Utility | Apple |
| .XIX | Microsoft Corporation | Gegevensbestanden | IIS NNTP Subject Lists | Microsoft Internet Information Services (IIS) | Microsoft Corporation |
| .XKM | Open Source | Gegevensbestanden | X KeyBoard File | Linux | Open Source |
| .XLC | Microsoft Corporation | Gegevensbestanden | Excel Chart | Microsoft Excel | Microsoft Corporation |
| .XLF | Open Source | Gegevensbestanden | XLIFF Document | Apple TextEdit | Apple |
| .XLG | Autodesk, Inc. | Gegevensbestanden | AutoCAD External Reference Log | Autodesk AutoCAD | Autodesk, Inc. |
| .XLGC | Prosystech | Gegevensbestanden | ExpressK Database File | Prosystech ExpressK | Prosystech |
| .XLO | Autodesk, Inc. | Gegevensbestanden | Autodesk Inventor Export Journal Data | Autodesk Inventor | Autodesk, Inc. |
| .XLT | Microsoft Corporation | Gegevensbestanden | Excel Template File | Microsoft Excel | Microsoft Corporation |
| .XLW | Microsoft Corporation | Gegevensbestanden | Microsoft Excel Workspace | Microsoft Excel | Microsoft Corporation |
| .XLZ | CPT | Gegevensbestanden | Crossword Power Tools Crossword Library File | Crossword Power Tools | CPT |
| .XM3 | Examiner Corporation | Gegevensbestanden | Examiner Corporation Assessment Item Bank | Examiner System | Examiner Corporation |
| .XMAP | XMind | Gegevensbestanden | XMind 2007/2008 Workbook | XMind | XMind |
| .XMAS | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .XMCD | Parametric Technology Corporation | Gegevensbestanden | Mathcad Worksheet File | PTC Mathcad Prime | PTC |
| .XMD | Bitdefender | Gegevensbestanden | Bitdefender Plugin File | Bitdefender Total Security 2018 | Bitdefender |
| .XMEF | LexisNexis | Gegevensbestanden | TextMap Evidence Format File | TextMap | LexisNexis |
| .XMI | Object Management Group (OMG) | Gegevensbestanden | XML Metadata Interchange File | Eclipse IDE for Java Developers | The Eclipse Foundation |
| .XMIT | IBM | Gegevensbestanden | IBM XMIT Data | Unknown Software | Unknown Developer |
| .XML | Wattle Software | Gegevensbestanden | XML File | MacroMates TextMate | MacroMates |
| .XMN | Sergei Andrzeevsky | Gegevensbestanden | Sprintometer Document | Sprintometer Pro | Sergei Andrzeevsky |
| .XMP | Adobe Systems Incorporated | Gegevensbestanden | Extensible Metadata Platform File | Microsoft Notepad | Microsoft Corporation |
| .XMPSES | Adobe Systems Incorporated | Gegevensbestanden | Adobe Premiere Elements Data | Adobe Premiere Elements | Adobe Systems Incorporated |
| .XMS | Alexander Gross | Gegevensbestanden | Music Studio Project | Alexander Gross Music Studio | Alexander Gross |
| .XMX | Autodesk, Inc. | Gegevensbestanden | AutoCAD External Message Compiled Data | Autodesk AutoCAD | Autodesk, Inc. |
| .XMZ | Starbreeze Studios | Gegevensbestanden | FastTracker 2 Extended Module | ModPlug Player | Open Source |
| .XNV | PeopleSoft | Gegevensbestanden | nVision Layout File | PS/nVision | PeopleSoft |
| .XPB | Tony D. Jones | Gegevensbestanden | XPB! Basic Source Code | XPB! Basic | Tony D. Jones |
| .XPF | Open Source | Gegevensbestanden | Linux MultiMedia Studio Preset File | LMMS | Open Source |
| .XPJ | Adobe Systems Incorporated | Gegevensbestanden | RoboHelp HTML Project | Adobe RoboHelp | Adobe Systems Incorporated |
| .XPK | THQ Nordic | Gegevensbestanden | WWE RAW Model File | Cygnus Hex Editor | SoftCircuits |
| .XPM | XnSoft | Gegevensbestanden | X11 Pixmap Graphic | GIMP | The GIMP Development Team |
| .XPO | Microsoft Corporation | Gegevensbestanden | Microsoft Dynamics AX Export File | Microsoft Dynamics AX | Microsoft Corporation |
| .XPR | Parametric Technology Corporation | Gegevensbestanden | Pro/ENGINEER Part Instance Accelerator File | Dassault Systemes SolidWorks | Dassault Systèmes |
| .XPS | Microsoft Corporation | Gegevensbestanden | Microsoft XPS (XML Paper Specification) File | Nuance Power PDF Professional | Nuance |
| .XPT | Mozilla | Gegevensbestanden | Mozilla Firefox Component | Mozilla Firefox | Mozilla |
| .XPW | Intercon Associates | Gegevensbestanden | Accessible FormNet Fillable Form File | Accessible FormNet | Intercon Associates |
| .XPX | Intercon Associates | Gegevensbestanden | Intercon FormNet File | Accessible FormNet | Intercon Associates |
| .XR2 | Open Source | Gegevensbestanden | Xrecode II Registration | Xrecode | Open Source |
| .XRB | XMind | Gegevensbestanden | XMind Resource Bundle | XMind | XMind |
| .XRDML | PANalytical | Gegevensbestanden | XRDML Data File | Panalytical Data Collector | Malvern Instruments Ltd |
| .XREF | IBM | Gegevensbestanden | IBM AIX Cross-Reference Data | IBM AIX | IBM |
| .XRF | Open Source | Gegevensbestanden | Cal3D XML Materials File | Cal3DViewer | Open Source |
| .XRFF | University of Waikato | Gegevensbestanden | Extensible Attribute-Relation File Format | Weka | University of Waikato |
| .XRL | SAP | Gegevensbestanden | PowerDesigner Report File | Sybase PowerDesigner | SAP |
| .XRP | Stand By Soft | Gegevensbestanden | RationalPlan Project File | Stand By Soft RationalPlan | RationalPlan |
| .XRT | 4pi Analysis | Gegevensbestanden | EDX Spectrum Export File In Xraytor Format | RevolutionSEM | 4pi Analysis |
| .XRY | MSAB | Gegevensbestanden | XRY Data File | XRY | MSAB |
| .XSC | Microsoft Corporation | Gegevensbestanden | Visual Studio Dataset Internal Info File | Microsoft Visual Studio | Microsoft Corporation |
| .XSEND | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .XSF | Microsoft Corporation | Gegevensbestanden | InfoPath Form Definition File | Microsoft InfoPath | Microsoft Corporation |
| .XSL | Syncro Soft | Gegevensbestanden | XML eXtensible Stylesheet | Microsoft Notepad | Microsoft Corporation |
| .XSLT | Syncro Soft | Gegevensbestanden | XSL Transformation File | Microsoft Notepad | Microsoft Corporation |
| .XSR | Bentley Systems | Gegevensbestanden | Bentley GEOPAK XS List Report | GEOPAK Civil Engineering Suite | Bentley Systems |
| .XSW | Milinta | Gegevensbestanden | Milinta APL Transfer Function File | Milinta APL | Milinta |
| .XTE | PerkinElmer | Gegevensbestanden | LabChip XTe Data | Unknown Software | Unknown Developer |
| .XTG | Ben Stöver | Gegevensbestanden | Extensible TreeGraph File | TreeGraph | Ben Stöver |
| .XTM | Institute for Human and Machine Cognition (IHMC) | Gegevensbestanden | CmapTools Exported Topic Map | IHMC CmapTools | Institute for Human and Machine Cognition (IHMC) |
| .XTP | adnx | Gegevensbestanden | xTime Project Document | xPlan | adnx |
| .XTP2 | Microsoft Corporation | Gegevensbestanden | Microsoft InfoPath Template | Microsoft InfoPath | Microsoft Corporation |
| .XTS | The U.S. Census Bureau | Gegevensbestanden | Integrated Microcomputer Processing System (IMPS) Data File | IMPS | The U.S. Census Bureau |
| .XVO | Open Source | Gegevensbestanden | RatDVD Internal File | RatDVD | Open Source |
| .XVU | Comodo Group | Gegevensbestanden | BOClean Database File | BOClean | Comodo Group |
| .XWF | Nuance | Gegevensbestanden | OmniPage Workflow File | OmniPage | Nuance |
| .XWZ | Major Geeks | Gegevensbestanden | X-Setup Pro Data File | X-Setup Pro | Major Geeks |
| .XXA | Brixx Software | Gegevensbestanden | Account Detail Chart File | Brixx | Brixx Software |
| .XXC | CentraLine | Gegevensbestanden | Centraline COACH Controller Firmware | Unknown Software | Unknown Developer |
| .XXD | Brixx Software | Gegevensbestanden | Brixx Planner Calendar | Brixx | Brixx Software |
| .XXP | Brixx Software | Gegevensbestanden | Plan File | Brixx | Brixx Software |
| .XXXX | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .XYT | Casa Software Ltd | Gegevensbestanden | PSU Bio Time-of-Flight Data | CasaXPS | Casa Software Ltd |
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