| .DIST | Apple | Gegevensbestanden | Mac OS X Distribution Script | MacroMates TextMate | MacroMates |
| .DISTZ | Apple | Gegevensbestanden | Apple Mac OS X Installer Distribution File | Apple OS X | Apple |
| .DIX | Robert Hijmans | Gegevensbestanden | DIVA-GIS Export File | DIVA-GIS | Robert Hijmans |
| .DJM | Dynojet Research | Gegevensbestanden | Dynojet Map File | Dynoject Research Power Commander Control Center | Dynojet Research |
| .DKL | Oleksandr TR Roslov | Gegevensbestanden | DupKiller File List | DupKiller | Oleksandr TR Roslov |
| .DKT | d-lusion interactive media | Gegevensbestanden | DiGiTIAL THUNDER Drum Kit File | Drum Station | d-lusion interactive media |
| .DL0 | ABBYY | Gegevensbestanden | Abbyy Finereader 4.0 Sprint Data | ABBYY FineReader | ABBYY |
| .DLC | JDownloader Team | Gegevensbestanden | Download Link Container File | JDownloader | JDownloader Team |
| .DLD | Campbell Scientific | Gegevensbestanden | EdLog Compiled Program | LoggerNet | Campbell Scientific |
| .DLG | Crytek | Gegevensbestanden | Crysis Dialogue Data File | Crysis | Crytek |
| .DLI | Interscape | Gegevensbestanden | Win32.Sober.AD@mm File | Win32.Sober.AD@mm | Interscape |
| .DLR | cebas Visual Technology | Gegevensbestanden | FinalRender Plugin | cebas Visual Technology finalRender | cebas Visual Technology |
| .DLT | Alstom | Gegevensbestanden | VCTEditor Data | VCTEditor | Alstom |
| .DLW | Dalim Software | Gegevensbestanden | DALiM LiTHO Line Work Bitmap | DALiM LiTHO | Dalim Software |
| .DLY | Xilinx, Inc. | Gegevensbestanden | Xilinx ISE ReportGen Delay Information | ISE Design Suite | Xilinx, Inc. |
| .DLZ | CPT | Gegevensbestanden | Crossword Power Tools Crossword Library File | Crossword Power Tools | CPT |
| .DM2 | Interscape | Gegevensbestanden | Toad Data Modeler 2 File | Toad Data Modeler | Interscape |
| .DMC | nModal Solutions Inc. | Gegevensbestanden | Datamartist Data Canvas File | nModal Solutions Datamartist | nModal Solutions Inc. |
| .DMD | Oracle Corporation | Gegevensbestanden | SQL Developer Data Modeler File | SQL Developer Data Model | Oracle Corporation |
| .DME | Interscape | Gegevensbestanden | Medical Manager DML System Merged Data | Medical Manager DML System | Emdeon Business Services, LLC |
| .DMG | Apple | Gegevensbestanden | Mac OS X Disk Image File | 7-Zip | Igor Pavlov |
| .DMI | BYOND | Gegevensbestanden | BYOND Dream Maker Icon File | BYOND | BYOND |
| .DML | Sybase, Inc | Gegevensbestanden | DynaScript File | Internet Explorer | Microsoft Corporation |
| .DMM | Seavus | Gegevensbestanden | iMindQ Mind Map File | Seavus iMindQ | Seavus |
| .DMO | Wouter van Oortmerssen | Gegevensbestanden | Cube 2: Sauerbraten Demo File | Cube 2 Sauerbraten | Open Source |
| .DMP | Microsoft Corporation | Gegevensbestanden | Windows Memory Dump File | Microsoft Visual Studio | Microsoft Corporation |
| .DMR | Brain Innovation | Gegevensbestanden | BrainVoyager Diffusion Weighted Project File | BrainVoyager QX | Brain Innovation |
| .DMW | ScienceScope | Gegevensbestanden | Datamass Ag File | Datamass Ag | ScienceScope |
| .DMY | PhysioNet | Gegevensbestanden | SEMIA LTST DB Time Series Data File | SEMIA | PhysioNet |
| .DNA | GSL Biotech LLC | Gegevensbestanden | SnapGene DNA File | SnapGene | GSL Biotech LLC |
| .DNC | Microsoft Corporation | Gegevensbestanden | Windows Dancer File | Windows Media Center | Microsoft Corporation |
| .DND | European Bioinformatics Institute | Gegevensbestanden | ClustalW2 Tree Data | ClustalW2 | European Bioinformatics Institute |
| .DNG | Adobe Systems Incorporated | Gegevensbestanden | Digital Negative Image File | MacPhun ColorStrokes | Macphun |
| .DNT | Rockwell Automation Inc. | Gegevensbestanden | RSNetWorx Project | RSNetWorx | Rockwell Automation Inc. |
| .DOCKZIP | Stardock Corporation | Gegevensbestanden | ObjectDock File | Stardock ObjectDock | Stardock Corporation |
| .DOD | Progress Software Corporation | Gegevensbestanden | Progress Artix Data Services Data Model | Progress Artix Data Services | Progress Software Corporation |
| .DOE | Rockwell Automation Inc. | Gegevensbestanden | Rockwell Arena Model File | Rockwell Arena Simulation | Rockwell Automation Inc. |
| .DOI | Actuate Corporation | Gegevensbestanden | BiRT Data Object Instance File | BIRT | Open Source |
| .DON | Apache Software Foundation | Gegevensbestanden | Apache OpenOffice (OpenOffice.org) Log | Apache OpenOffice | Apache Software Foundation |
| .DOP | DxO Labs | Gegevensbestanden | DxO Optics Pro Correction Settings File | DxO OpticsPro | DxO Labs |
| .DOT | Microsoft Corporation | Gegevensbestanden | Word Document Template | Apache OpenOffice | Apache Software Foundation |
| .DOV | Safer Networking Ltd. | Gegevensbestanden | Temporary (Temp) File | FileAlyzer | Safer Networking Ltd. |
| .DOWN | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DOX | Microsoft Corporation | Gegevensbestanden | Visual Basic Binary UserDocument | Microsoft Visual Studio | Microsoft Corporation |
| .DP | Stefan Hagel | Gegevensbestanden | Text Document | Microsoft Notepad | Microsoft Corporation |
| .DP4 | Apian Software | Gegevensbestanden | DecisionPad 4 Project | DecisionPad | Apian Software |
| .DPB | Susteen, Inc. | Gegevensbestanden | DataPilot Backup File | DataPilot | Susteen, Inc. |
| .DPC | Microsoft Corporation | Gegevensbestanden | Microsoft Office Resource File | Microsoft Office | Microsoft Corporation |
| .DPD | David Pilling | Gegevensbestanden | Ovation Pro File | Ovation Pro Reader | David Pilling |
| .DPE | Procedimientos-Uno, S.L. | Gegevensbestanden | DPwinEHE Project File | DPwinEHE | Interscape |
| .DPF | Open Source | Gegevensbestanden | Dargon Package | Dargon | Open Source |
| .DPJ | Delft Spline Systems | Gegevensbestanden | DeskProto Project | DeskProto | Delft Spline Systems |
| .DPN | Depiction Inc. | Gegevensbestanden | Depiction Data File | Depiction | Depiction Inc. |
| .DPO | DECAdry | Gegevensbestanden | DECAdry Express Business Cards Business Card | DECAdry Express Business Cards | DECAdry |
| .DPS | DivX, LLC. | Gegevensbestanden | DivX Player 2 Skin File | DivX | DivX, LLC. |
| .DPT | Kingsoft | Gegevensbestanden | Kingsoft Presentation Template | Kingsoft Office | Kingsoft |
| .DPX | Kodak | Gegevensbestanden | Digital Picture Exchange File | Adobe SpeedGrade | Adobe Systems Incorporated |
| .DQC | Open Source | Gegevensbestanden | CP/M Disk Information Data | CP/M | Open Source |
| .DR | Sony Mobile Communications | Gegevensbestanden | DRM Rights Object | DRM Packager | Sony Mobile Communications |
| .DRAFT | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DRB | Dr. Software | Gegevensbestanden | Dr. Beam Pro Data | Dr. Beam Pro | Dr. Software |
| .DRC | Open Source | Gegevensbestanden | Open Mobile Alliance DRM Rights Object | Microsoft Notepad | Microsoft Corporation |
| .DRE | DÖRR EDV-Beratung | Gegevensbestanden | DReport Exported Report | DReport | DÖRR EDV-Beratung |
| .DRIVE | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DRIVERS | Apple | Gegevensbestanden | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .DRL | Gerber Technology | Gegevensbestanden | Gerber Drill Rack File | Altium Designer | Altium |
| .DRN | Unknown Developer | Gegevensbestanden | Darn for DOS Data File | Darn software | Unknown Developer |
| .DRO | Open Source | Gegevensbestanden | DOSBox Raw OPL Format | DOSBox | Open Source |
| .DRT | Micrografx | Gegevensbestanden | Micrografix Windows Draw Template File | Micrografix Windows Draw | Micrografx |
| .DRX | Adobe Systems Incorporated | Gegevensbestanden | Adobe Photoshop Tutorial Data | Adobe Photoshop | Adobe Systems Incorporated |
| .DRY | Unknown Developer | Gegevensbestanden | XAIRON Organizer Diary File | XAIRON Organizer | Unknown Developer |
| .DRZ | Unknown Developer | Gegevensbestanden | Draz Paint File | XnView MP | XnSoft |
| .DS | DAZ 3D | Gegevensbestanden | DAZ Studio 1/2 Script | DAZ Studio | DAZ 3D |
| .DSB | Dell Technologies | Gegevensbestanden | Dell DataSafe Backup File | DataSafe Local Backup | Dell Technologies |
| .DSC | Kingsoft | Gegevensbestanden | Kingsoft Design Science Equation File | Kingsoft Office | Kingsoft |
| .DSD | Autodesk, Inc. | Gegevensbestanden | AutoCAD Drawing Set Description File | Autodesk AutoCAD | Autodesk, Inc. |
| .DSE | DAZ 3D | Gegevensbestanden | DAZ Studio Encrypted Script | DAZ Studio | DAZ 3D |
| .DSHADER | Microsoft Corporation | Gegevensbestanden | Microsoft Visual Studio Text Data | Microsoft Visual Studio | Microsoft Corporation |
| .DSL | ABBYY | Gegevensbestanden | Lingvo Dictionary Data File | ABBYY Lingvo Dictionary | ABBYY |
| .DSR | Activision | Gegevensbestanden | Modern Warfare 3 Dedicated Server Recipe File | Call of Duty 4: Modern Warfare | Activision |
| .DSSLIDESHOW | Idea2 s.c. | Gegevensbestanden | Desktop Sidebar Slideshow Panel File | Desktop Sidebar | Idea2 s.c. |
| .DSX | DAZ 3D | Gegevensbestanden | DAZ Studio XML File | DAZ Studio | DAZ 3D |
| .DSY | Lead System (M) Sdn. Bhd. | Gegevensbestanden | Besta Video File | Besta Electronic Dictionaries | Lead System (M) Sdn. Bhd. |
| .DSZ | Orchida Soft | Gegevensbestanden | Orchida (OES) Embroidery File | Orchida Embroidery System | Orchida Soft |
| .DT | d-lusion interactive media | Gegevensbestanden | Drum Station Machine State File | Drum Station | d-lusion interactive media |
| .DT? | Terry A. Davis | Gegevensbestanden | LoseThos Data File | LoseThos | Terry A. Davis |
| .DTA | IWIS | Gegevensbestanden | Chain Engineering Database | Chain Engineering | IWIS |
| .DTC | Microsoft Corporation | Gegevensbestanden | Windows Application Log File | Microsoft Windows Millenium Edition | Microsoft Corporation |
| .DTD | Syncro Soft | Gegevensbestanden | Document Type Definition File | Microsoft Notepad | Microsoft Corporation |
| .DTE | DoroTree Technologies | Gegevensbestanden | DoroTree Family Tree Data | DoroTree | DoroTree Technologies |
| .DTERMLICENCE | Decimus Software, Inc. | Gegevensbestanden | DTerm Licence File | DTerm | Decimus Software, Inc. |
| .DTH | Microsoft Corporation | Gegevensbestanden | Microsoft Windows Application Log File | Microsoft Windows | Microsoft Corporation |
| .DTI | Microsoft Corporation | Gegevensbestanden | Microsoft Windows Application Log File | Microsoft Windows | Microsoft Corporation |
| .DTM | Prodatron | Gegevensbestanden | DigiTrakker Audio Module | CocoModX | Open Source |
| .DTR | Swisslog | Gegevensbestanden | Swisslog Downtime Analyzer Report | Unknown Software | Unknown Developer |
| .DUMP | Microsoft Corporation | Gegevensbestanden | Dump File | macOS | Apple |
| .DUT | Microsoft Corporation | Gegevensbestanden | Dutch Localization Language | Microsoft Notepad | Microsoft Corporation |
| .DVC | IBM | Gegevensbestanden | Lotus 1-2-3 Data | Lotus 1-2-3 | IBM |
| .DVDFABHDDECRYPTER | Fengtao Software Inc. | Gegevensbestanden | DVDFab HD Decrypter File | DVDFab HD Decrypter | Fengtao Software Inc. |
| .DVDFABPLATINUM5 | Fengtao Software Inc. | Gegevensbestanden | DVDFab Platinum File | DVDFab | Fengtao Software Inc. |
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