| .DAE | Sony | Fichiers 3D | Digital Asset Exchange File | Adobe Photoshop CC | Adobe Systems Incorporated |
| .DATA | Appricon | Fichiers de données | Analysis Studio Offline Data | Adobe Soundbooth | Adobe Systems Incorporated |
| .DBF | dBase, LLC | Fichiers de base de données | Database File | JetForm FormFlow | Adobe Systems Incorporated |
| .DBM | Adobe Systems Incorporated | Fichiers Web | ColdFusion Server File | Adobe ColdFusion Builder | Adobe Systems Incorporated |
| .DC2 | Kodak | Fichiers Raster Image | Kodak Digital Camera RAW Image File | Adobe Photoshop | Adobe Systems Incorporated |
| .DCM | National Electrical Manufacturers Association (NEMA) | Fichiers Raster Image | DICOM Image File Format | Adobe Photoshop | Adobe Systems Incorporated |
| .DCP | Embarcadero Technologies | Fichiers de développeurs | Delphi Compiled Package | Adobe Photoshop CC | Adobe Systems Incorporated |
| .DCS | Quark Software Inc. | Fichiers d’image vectorielle | Desktop Color Separation File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DCX | ZSoft Corporation | Fichiers Raster Image | Zsoft Multi-Page Paintbrush File | Adobe Photoshop | Adobe Systems Incorporated |
| .DDS | Microsoft Corporation | Fichiers Raster Image | DirectDraw Surface | Adobe Photoshop | Adobe Systems Incorporated |
| .DEU | Adobe Systems Incorporated | Fichiers de données | Adobe Reader German Language File | Adobe Reader | Adobe Systems Incorporated |
| .DFM | Open Source | Fichiers textes | Pascal File | ExtendScript Toolkit (ESTK) | Adobe Systems Incorporated |
| .DHY | Adobe Systems Incorporated | Fichiers de données | Adobe Bridge Information File | Adobe Bridge CC | Adobe Systems Incorporated |
| .DIB | The GIMP Development Team | Fichiers Raster Image | Device Independent Bitmap File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DIM | Active@ Data Recovery Software | Fichiers de sauvegarde | Active@ Raw Disk Image Backup File | Adobe Dimensions | Adobe Systems Incorporated |
| .DIR | Adobe Systems Incorporated | Fichiers vidéo | Adobe Director Movie | Adobe Director | Adobe Systems Incorporated |
| .DLG | Crytek | Fichiers de jeu | Crysis Dialogue Data File | ExtendScript Toolkit (ESTK) | Adobe Systems Incorporated |
| .DLM | AKAMAI | Fichiers divers | Akamai Download Manager File | Adobe Creative Cloud | Adobe Systems Incorporated |
| .DLV | Dassault Systèmes | Fichiers CAD | CATIA 4 Export File | Adobe Acrobat DC | Adobe Systems Incorporated |
| .DLX | DIAL | Fichiers CAD | DIALux Document | Adobe Premiere Pro CC | Adobe Systems Incorporated |
| .DMV | Adobe Systems Incorporated | Fichiers de paramètres | Adobe Acrobat Catalog Data | Adobe Acrobat DC | Adobe Systems Incorporated |
| .DNG | Adobe Systems Incorporated | Fichiers Raw 'appareil photo | Digital Negative Image File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .DOG | Ubisoft Blue Byte | Fichiers de jeu | Dogz Dog Description File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .DPX | Kodak | Fichiers Raster Image | Digital Picture Exchange File | Adobe SpeedGrade | Adobe Systems Incorporated |
| .DRT | Micrografx | Fichiers graphiques | Micrografix Windows Draw Template File | Adobe Director | Adobe Systems Incorporated |
| .DRX | Adobe Systems Incorporated | Fichiers de données | Adobe Photoshop Tutorial Data | Adobe Photoshop | Adobe Systems Incorporated |
| .DV | Roxio | Fichiers vidéo | Digital Video File | Adobe Flash Professional CC | Adobe Systems Incorporated |
| .DWG | Autodesk, Inc. | Fichiers CAD | AutoCAD Drawing Database File | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DWS | Autodesk, Inc. | Fichiers CAD | AutoCAD Drawing Standards File | Adobe Dreamweaver | Adobe Systems Incorporated |
| .DWT | Adobe Systems Incorporated | Fichiers Web | Dreamweaver Web Page Template | Adobe Dreamweaver | Adobe Systems Incorporated |
| .DXF | Autodesk, Inc. | Fichiers CAD | Drawing Exchange Format | Adobe Illustrator CC | Adobe Systems Incorporated |
| .DXR | Adobe Systems Incorporated | Fichiers vidéo | Protected Macromedia Director Movie | Adobe Director | Adobe Systems Incorporated |
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