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| Extension | File Type Developer | File Category | File Type Description | Primary Software | Primary Software Developer |
|---|---|---|---|---|---|
| .UAP | Siemens AG | Settings Files | SIMATIC WinCC User Archive Export | TIA Portal | Siemens AG |
| .UBB | Oracle Corporation | Settings Files | BEA eLink Adapter Configuration Data | BEA eLink Adapter | Oracle Corporation |
| .UCF | Cisco Systems | Settings Files | WebEx Media File | WebEx Meetings | Cisco Systems |
| .UCI | SysDevSoftware | Settings Files | UFS Explorer Backup File | SysDevSoftware UFS Explorer | SysDevSoftware |
| .UCX | IBM | Settings Files | Rational XDE Data | Rational Rose | IBM |
| .UIS | Stardock Corporation | Settings Files | WindowBlinds User Interface Specification | WindowBlinds | Stardock Corporation |
| .UL | Microsoft Corporation | Settings Files | Windows Updates Downloader Update List File | Windows Updates Downloader | Microsoft Corporation |
| .ULF | MRF GeoSystems | Settings Files | Universal List File | MRF Mapping Tool Kit | MRF GeoSystems |
| .ULZ | Microsoft Corporation | Settings Files | Windows Updates Downloader Update List File | Windows Updates Downloader | Microsoft Corporation |
| .UMB | Microsoft Corporation | Settings Files | MemMaker Backup Archive | MS-DOS | Microsoft Corporation |
| .UPD | Various Developers | Settings Files | Program Update Information | Microsoft Notepad | Microsoft Corporation |
| .UPF | Bentley Systems | Settings Files | MicroStation User Preferences File | MicroStation | Bentley Systems |
| .URF | Matinsoft Inc. | Settings Files | AppFace Skin File | AppFace User Interface Development Kits | Matinsoft Inc. |
| .URS | ControlDraw Ltd. | Settings Files | ControlDraw User Requirement Specifier | ControlDraw | ControlDraw Ltd. |
| .USER | Microsoft Corporation | Settings Files | Visual Studio Project User Options File | Microsoft Notepad | Microsoft Corporation |
| .USF | EVGA Corporation | Settings Files | EVGA Precision X Skin File | EVGA PrecisionX | EVGA Corporation |
| .USR | FileMaker Inc. | Settings Files | FileMaker Pro Database File | FileMaker Pro | FileMaker Inc. |
| .UTI | BioWare | Settings Files | Bioware Aurora Item Data | BioWare Neverwinter Nights | BioWare |
| .UTS | BioWare | Settings Files | BioWare Aurora Game Engine Sound File | BioWare Neverwinter Nights | BioWare |
| .UVOPT | Keil | Settings Files | µVision Project Options | µVision4 | Keil |
| .UVOPTX | Keil | Settings Files | µVision Configuration | µVision4 | Keil |
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