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| Extension | File Type Developer | File Category | File Type Description | Software | Software Developer |
|---|---|---|---|---|---|
| .DAE | Sony | 3D Image Files | Digital Asset Exchange File | GLC_Player | Open Source |
| .DAR | Open Source | Compressed Files | DAR Disk Archive File | DAR (Disk Archive) | Open Source |
| .DAT | Unknown Developer | Game Files | Game Data | Dragon UnPACKer | Open Source |
| .DATA | Appricon | Data Files | Analysis Studio Offline Data | Linux | Open Source |
| .DAX | Open Source | Disk Image Files | PSP Compressed ISO Disc Image | UMDGen | Open Source |
| .DB | Dwayne Richard Hipp | Database Files | Mobile Device Database File | GTK DBF Editor | Open Source |
| .DBF | dBase, LLC | Database Files | Database File | GTK DBF Editor | Open Source |
| .DBP | Microsoft Corporation | Developer Files | Microsoft Visual Studio Visual C++ Database Project | Nvu | Open Source |
| .DC2 | Kodak | Raster Image Files | Kodak Digital Camera RAW Image File | Darktable | Open Source |
| .DCF | Sony Mobile Communications | Audio Files | DRM Content Format File | Safetica Free | Open Source |
| .DCM | National Electrical Manufacturers Association (NEMA) | Raster Image Files | DICOM Image File Format | IrfanView | Open Source |
| .DCO | Safetica Technologies | Encoded Files | Safetica Free Encrypted Virtual Disk Archive | Safetica Free | Open Source |
| .DCT | Microsoft Corporation | Data Files | Dictionary File | DeSmuME | Open Source |
| .DCTMP | Open Source | Uncommon Files | DC++ Partially Downloaded File | DC++ | Open Source |
| .DCX | ZSoft Corporation | Raster Image Files | Zsoft Multi-Page Paintbrush File | IrfanView | Open Source |
| .DDS | Microsoft Corporation | Raster Image Files | DirectDraw Surface | IrfanView | Open Source |
| .DDT | Sports Interactive | Game Files | Football Manager Keep Player Data File | Linux | Open Source |
| .DEBIAN | Debian | Data Files | Debian Related File | Debian software (dpkg) | Open Source |
| .DEI | Open Source | Data Files | Gerber Design Engineered Interface | Gerbv | Open Source |
| .DEM | Valve | Game Files | Video Game Demo File | VirtualDub | Open Source |
| .DEMO | Open Source | Game Files | Pokemon Type Wild Data File | Pokémon Type Wild | Open Source |
| .DFAC | Unknown Developer | Developer Files | DreamFactory ActiveX Control | DreamFactory | Open Source |
| .DFC | Jenner Fusari | Audio Files | Defractor Instrument | DeSmuME | Open Source |
| .DFD | Open Source | Developer Files | ABC Dyadic Functions Data | ABC Programming langauge | Open Source |
| .DFF | Zanoza Software | 3D Image Files | RenderWare Model File | Audacity | Open Source |
| .DFONT | Open Source | Font Files | Mac OS X Data Fork Font | DFONTSplitter | Open Source |
| .DFS | Open Source | 3D Image Files | BrainSuite Surface File | BrainSuite | Open Source |
| .DGD | Unknown Developer | Developer Files | DGD Program | Dworkin's Game Driver | Open Source |
| .DIF | Microsoft Corporation | Data Files | Data Interchange Format | Gnumeric | Open Source |
| .DISK | Open Source | Disk Image Files | Linux Virtual Hard Disk | Linux | Open Source |
| .DIX | Robert Hijmans | GIS Files | DIVA-GIS Export File | Stonevoice Translator | Open Source |
| .DIZ | Unknown Developer | Text Files | Description In Zip File | AbiWord | Open Source |
| .DJV | LizardTech | Raster Image Files | DjVu Compressed Image Format | WinDjView | Open Source |
| .DJVU | LizardTech | Raster Image Files | DjVu Image | WinDjView | Open Source |
| .DMAP | Open Source | Game Files | Conquer Online 2 Game Map | Conquer Online 2 | Open Source |
| .DMF | Geosystem | GIS Files | Geosystem Digitals Map File | ModPlug Player | Open Source |
| .DMG | Apple | Disk Image Files | Mac OS X Disk Image File | PeaZip | Open Source |
| .DML | Sybase, Inc | Web Files | DynaScript File | Amaya | Open Source |
| .DMO | Wouter van Oortmerssen | Game Files | Cube 2: Sauerbraten Demo File | Cube 2 Sauerbraten | Open Source |
| .DNA | GSL Biotech LLC | Data Files | SnapGene DNA File | BioPerl | Open Source |
| .DNS | 3D Realms | Game Files | Duke Nukem Forever Save File | DynSite | Open Source |
| .DOC | Microsoft Corporation | Text Files | Microsoft Word Document (before The 2007 Version) | Tiki Wiki CMS Groupware | Open Source |
| .DOI | Actuate Corporation | Data Files | BiRT Data Object Instance File | BIRT | Open Source |
| .DOK | Nenad Hrg | Settings Files | DesktopOK Icons Layout File | Notepad2 | Open Source |
| .DOX | Microsoft Corporation | Developer Files | Visual Basic Binary UserDocument | Doxygen | Open Source |
| .DPD | David Pilling | Page Layout Files | Ovation Pro File | ABC Programming langauge | Open Source |
| .DPF | Open Source | Game Files | Dargon Package | Dargon | Open Source |
| .DPG | Open Source | Video Files | Nintendo DS Movie File | MoonShell | Open Source |
| .DPR | Niklaus Wirth | Developer Files | Pascal Source Code | Free Pascal | Open Source |
| .DQC | Open Source | Data Files | CP/M Disk Information Data | CP/M | Open Source |
| .DRO | Open Source | Audio Files | DOSBox Raw OPL Format | DOSBox | Open Source |
| .DS | DAZ 3D | 3D Image Files | DAZ Studio 1/2 Script | LMMS | Open Source |
| .DSC | Kingsoft | Settings Files | Kingsoft Design Science Equation File | Celestia | Open Source |
| .DSF | DAZ 3D | 3D Image Files | DAZ Studio Asset File | ModPlug Player | Open Source |
| .DSL | ABBYY | Data Files | Lingvo Dictionary Data File | Media Player Classic | Open Source |
| .DSM | Open Source | Audio Files | Digital Sound Module | ModPlug Player | Open Source |
| .DSP | Open Source | Audio Files | Dynamic Studio Professional Module | ModPlug Player | Open Source |
| .DST | Autodesk, Inc. | CAD Files | AutoCAD Sheet Set File | Embroidermodder 2 | Open Source |
| .DSV | Open Source | Game Files | DeSmuME Saved Game File | DeSmuME | Open Source |
| .DTD | Syncro Soft | Developer Files | Document Type Definition File | Notepad2 | Open Source |
| .DTM | Prodatron | Audio Files | DigiTrakker Audio Module | CocoModX | Open Source |
| .DTX | Open Source | Page Layout Files | Documented LaTeX File | Lyx | Open Source |
| .DUCK | Open Source | Settings Files | Cyberduck Bookmark | Cyberduck | Open Source |
| .DVI | The Evince Team | Text Files | Device Independent Format File | Lyx | Open Source |
| .DVM | Open Source | Video Files | DVM Movie File Format | DVM development kit | Open Source |
| .DW | Un4seen Developments | Audio Files | David Whittaker Audio File | DeliPlayer | Open Source |
| .DWI | KONAMI | Data Files | Dance With Intensity Song File | DWI Extreme | Open Source |
| .DWM | Open Source | CAD Files | Digital Works Circuit Project | Digital Works | Open Source |
| .DX | Digital Equipment Corporation | Text Files | DEC WPS Plus File | Notepad2 | Open Source |
| .DXF | Autodesk, Inc. | CAD Files | Drawing Exchange Format | Cheetah3D | Open Source |
| .DXL | IBM | Database Files | Domino XML Language File | gVim | Open Source |
| .DZ | Digital Extremes | Game Files | Land Of The Dead Level File | Dzip | Open Source |
| .E | OpenEuphoria | Developer Files | Euphoria Include File | Amiga E | Open Source |
| .E2P | Open Source | Data Files | PonyProg Device File | PonyProg | Open Source |
| .E32 | Jordan Russell | Data Files | Inno Setup 1.3 Data | Inno Setup | Open Source |
| .E3D | Macromedia | 3D Image Files | Macromedia Extreme 3D Object | EDGELIB | Open Source |
| .E57 | ASTM E57 Committee on 3D Imaging Systems | 3D Image Files | LIDAR Point Cloud Data File | libE57 | Open Source |
| .EBN | Philips 3D Solutions | Uncommon Files | Philips Firmware Update File | Windows Phone Device Manager | Open Source |
| .ECG | Open Source | Data Files | Electrocardiography Data | FreeECG | Open Source |
| .ECP | Intelitek | Developer Files | EasyC Project File | Ettercap | Open Source |
| .ECU | Open Source | Settings Files | TunerPro ECU Configurator Data | TunerPro | Open Source |
| .ECW | ESRI (Environmental Systems Research Institute) | Raster Image Files | Enhanced Compression Wavelet Image | IrfanView | Open Source |
| .ED2K | Open Source | Web Files | eDonkey Download Link | eMule | Open Source |
| .EDH | MindWare Technologies | Data Files | HRV Edit Data | xcontur | Open Source |
| .EDR | BALARAD | Settings Files | Embird Color Palette | Embroidermodder 2 | Open Source |
| .EEP | Open Source | Data Files | EEPROM Data File | PonyProg | Open Source |
| .EFG | Open Source | Developer Files | Gambit Extensive Game Format | Gambit | Open Source |
| .EID | IBM | Data Files | IBM Voice Type Languages Newuser File | Faena MyID | Open Source |
| .EK6 | Open Source | Game Files | Generation 6 Pokémon Save File | PKHeX | Open Source |
| .EKX | Open Source | Game Files | Encrypted 3DS Pokémon Save File | PKHeX | Open Source |
| .ELF | Nintendo | Executable Files | Nintendo Wii Game File | PCSX2 | Open Source |
| .ELM | Open Source | Game Files | Eternal Lands Map File | Eternal Lands | Open Source |
| .ELP | Open Source | Data Files | eXe Learning Package File | eXeLearning | Open Source |
| .EMF | Microsoft Corporation | Vector Image Files | Enhanced Windows Metafile | IrfanView | Open Source |
| .EMLX | Apple | Text Files | Apple Mail Message | PSPad | Open Source |
| .EMP | Open Source | Audio Files | eMusic Music Download File | eMusic/J | Open Source |
| .EMX | Open Source | Audio Files | eMusic Download File | eMusic/J | Open Source |
| .ENB | Open Source | Data Files | eNotebook Notebook File | eNotebook | Open Source |
| .ENC | Smith Micro Software | Encoded Files | Encoded Data File | ZipZag | Open Source |
| .ENCRYPTED | Malwarebytes | Encrypted Files | Crypt0L0cker Ransomware Infected Files | HandyBits EasyCrypto Deluxe | Open Source |
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