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| Extension | File Type Developer | File Category | File Type Description | Software | Software Developer |
|---|---|---|---|---|---|
| .U | Epic Games | Game Files | Unreal Tournament Class Package | Apple QuickTime Player | Apple |
| .UB | Waveform Software | Audio Files | Unsigned Byte Audio File | Apple QuickTime Player | Apple |
| .UBM | Apple | Uncommon Files | IPhoto Mtwain Install File | Apple iPhoto | Apple |
| .UG | Autodesk, Inc. | Vector Image Files | Drawing File | Apple AppleWorks | Apple |
| .UM | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .UNIVERSAL3 | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .UNLOCK | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .UNX | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .UP | Apple | Data Files | Golden Orchard Apple II CD Rom File | Apple OS X | Apple |
| .UPI | Ulead Systems | Graphic Files | Ulead PhotoImpact Plugin | Apple iPhoto | Apple |
| .URL | Microsoft Corporation | Web Files | Internet Shortcut | Apple TextEdit | Apple |
| .USAGE | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .USE | Unknown Developer | Text Files | Log File | Apple TextEdit | Apple |
| .USER | Microsoft Corporation | Settings Files | Visual Studio Project User Options File | Apple TextEdit | Apple |
| .UTILITY | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .UTMP | Unknown Developer | Data Files | Unknown Apple II File. (found On Golden Orchard Apple II CD Rom) | Apple IIGS | Apple |
| .UU | Open Source | Encoded Files | Uuencoded File | Apple Archive Utility | Apple |
| .UUE | Open Source | Encoded Files | Uuencoded File | Apple Archive Utility | Apple |
| .UW | Apple | Audio Files | Unsigned Word Audio File | Apple QuickTime Player | Apple |
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