| .RA1 | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RABBIT | Apple | Fișiere neobișnuite | Unknown Apple II File (Golden Orchard Apple II CD Rom) | Golden Orchard | DigiSoft Innovations |
| .RADIOREVOL | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RAINDROPPI | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RAL | Span Software | Fișiere neobișnuite | WinRail Track Design File | WinRail | Span Software |
| .RAMDISK | DigiSoft Innovations | Fișiere neobișnuite | An Unknown Apple II File | Golden Orchard | DigiSoft Innovations |
| .RASMOL | Roger Sayle | Fișiere neobișnuite | RasMol File | RasMol | SourceForge |
| .RASTERW | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RAT | World Wide Web Consortium (W3C) | Fișiere neobișnuite | PICS Rating File | Microsoft Notepad | Microsoft Corporation |
| .RAW_PPM | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RAZ | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RCE | Unknown Developer | Fișiere neobișnuite | NTgraph GUI Control 3D File | Unknown Software | Unknown Developer |
| .RCPROFILE | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RCV | Oracle Corporation | Fișiere neobișnuite | Oracle Recovery Manager Script | Oracle Database | Oracle Corporation |
| .RDB-SHM | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RDB2 | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RDM | Devolutions | Fișiere neobișnuite | Remote Desktop Manager Exported Entries | Remote Desktop Manager | Devolutions |
| .REALDOWNLO | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RECOVERYDA | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .REFER | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .REGDUMP | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .REI | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .REM | BlackBerry | Fișiere neobișnuite | BlackBerry Encrypted Data File | Research In Motion BlackBerry Desktop Manager | BlackBerry |
| .REN | Unknown Developer | Fișiere neobișnuite | Renamed File | Unknown Software | Unknown Developer |
| .REP?FB_XD_FRAGMENT= | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .REQ | Open Source | Fișiere neobișnuite | SSL Certificate Request File | Microsoft Exchange Server | Microsoft Corporation |
| .REQW | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RESONANCEI | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RESOURCESC | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RETURNTOOL | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RFB | Siber Systems | Fișiere neobișnuite | RoboForm Bookmark File | RoboForm | Siber Systems |
| .RFC1896 | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RFP | Siber Systems | Fișiere neobișnuite | RoboForm Passcard File | RoboForm | Siber Systems |
| .RFT | Autodesk, Inc. | Fișiere neobișnuite | Revit Family Template File | AutoCAD Architecture | Autodesk, Inc. |
| .RFX | Unknown Developer | Fișiere neobișnuite | TouchStar License | Unknown Software | Unknown Developer |
| .RGR | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RHC | RLIB Software | Fișiere neobișnuite | ClipX RLIB RHELP Source File | ClipX RLIB RHELP Source File' | RLIB Software |
| .RHT | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RIDEOFVALK | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RII | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RJS | Yukihiro “Matz” Matsumoto | Fișiere neobișnuite | Ruby Javascript File | Notepad++ | Don Ho |
| .RKA | Malcolm Taylor | Fișiere neobișnuite | RK Audio Compressed Data File | RKau, | Malcolm Taylor |
| .RLA | Wavefront Technologies | Fișiere neobișnuite | Alias/Wavefront Image File | XnView MP | XnSoft |
| .RLU | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RMF | Valve | Fișiere neobișnuite | Hammer Rich Map Format | Valve Hammer Editor | Valve |
| .RML | Autodesk, Inc. | Fișiere neobișnuite | Redline Markup Language File | Volo View | Autodesk, Inc. |
| .RND | Symantec Corporation | Fișiere neobișnuite | PGP Random Seed File | Pretty Good Privacy (PGP) | Symantec Corporation |
| .ROADS | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .ROM | Various Developers | Fișiere neobișnuite | Read Only Memory Image | Basilisk II | Open Source |
| .RPG | Open Source | Fișiere neobișnuite | Programming Language Source Code File | RPG Toolkit | Open Source |
| .RPNM | Pierre-Emmanuel Gougelet | Fișiere neobișnuite | Portable Image Image File | XnView MP | XnSoft |
| .RPP | Cockos Incorporated | Fișiere neobișnuite | REAPER Project | REAPER | Cockos Incorporated |
| .RPSS | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RPST | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RPTDOCUMEN | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RPTTEMPLAT | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RPU | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RQZ | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RSA | Various Developers | Fișiere neobișnuite | RSA Certificate File | Mozilla Firefox | Mozilla |
| .RTC | Brain Innovation | Fișiere neobișnuite | BrainVoyager QX Design Matrix File | BrainVoyager QX | Brain Innovation |
| .RTM | Unknown Developer | Fișiere neobișnuite | Real Tracker Module | Real Tracker | Unknown Developer |
| .RTP | KTH Royal Institute of Technology | Fișiere neobișnuite | Gromacs Residue Topology Parameter File | Gromacs | KTH Royal Institute of Technology |
| .RTX | The Document Foundation | Fișiere neobișnuite | Rich Text Document | LibreOffice | The Document Foundation |
| .RU) | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RV2 | Unknown Developer | Fișiere neobișnuite | Uncommon File Extension | Unknown Software | Unknown Developer |
| .RWJ | Unknown Developer | Fișiere neobișnuite | Unknown File Type | Unknown Software | Unknown Developer |
| .RWZ | Microsoft Corporation | Fișiere neobișnuite | Outlook Rules Wizard File | Microsoft Outlook 2016 | Microsoft Corporation |
| .RXC | Sonic Solutions | Fișiere neobișnuite | Roxio Certificate File | Roxio Creator NXT Pro 6 | Roxio |
| .RYS | Piotr Fusik | Fișiere neobișnuite | Mamut Picture Image File | Recoil | Piotr Fusik |
din 1 
