| .DOX | Microsoft Corporation | Ficheiros de Texto | Visual Basic Binary UserDocument | Microsoft Visual Studio | Microsoft Corporation |
| .DP | Stefan Hagel | Ficheiros de Texto | Text Document | Microsoft Notepad | Microsoft Corporation |
| .DPO | DECAdry | Ficheiros de Texto | DECAdry Express Business Cards Business Card | DECAdry Express Business Cards | DECAdry |
| .DROPBOX | Dropbox, Inc. | Ficheiros de Texto | Dropbox Shared Folder Tracker | Dropbox | Dropbox, Inc. |
| .DRP | DÖRR EDV-Beratung | Ficheiros de Texto | DReport Document | DReport | DÖRR EDV-Beratung |
| .DSC | Kingsoft | Ficheiros de Texto | Kingsoft Design Science Equation File | Kingsoft Office | Kingsoft |
| .DSO | Microsoft Corporation | Ficheiros de Texto | Microsoft Visual Studio Workspace Data | Microsoft Visual Studio | Microsoft Corporation |
| .DVI | The Evince Team | Ficheiros de Texto | Device Independent Format File | Evince | The Evince Team |
| .DWD | DiamondWare Ltd. | Ficheiros de Texto | DiamondWare Digital Audio File | Wi-Fone | DiamondWare Ltd. |
| .DX | Digital Equipment Corporation | Ficheiros de Texto | DEC WPS Plus File | Microsoft Notepad | Microsoft Corporation |
| .DXB | Autodesk, Inc. | Ficheiros de Texto | Drawing Exchange Binary | Autodesk AutoCAD | Autodesk, Inc. |
| .EDN | Xilinx, Inc. | Ficheiros de Texto | EDIF Implementation Netlist File | Xilinx ISE WebPACK | Xilinx, Inc. |
| .EDOC | EUSO | Ficheiros de Texto | Electronically Certified Document | EDOC Java Libraries | EUSO |
| .EGT | EagleGet | Ficheiros de Texto | EagleGet Temporary File | EagleGet | EagleGet |
| .EIM | EIAS3D | Ficheiros de Texto | Electric Image Model | Electric Image Animation System (EIAS) | EIAS3D |
| .EIO | Yozosoft | Ficheiros de Texto | Yozo Office File | Yozosoft Yozo Office | Yozosoft |
| .EIT | Yozosoft | Ficheiros de Texto | Yozo Office Template File | Yozosoft Yozo Office | Yozosoft |
| .EMD | FMJ-Software | Ficheiros de Texto | ABT Extended Module File | Awave Studio | FMJ-Software |
| .EMF | Microsoft Corporation | Ficheiros de Texto | Enhanced Windows Metafile | Apache OpenOffice | Apache Software Foundation |
| .EMLX | Apple | Ficheiros de Texto | Apple Mail Message | Notepad++ | Don Ho |
| .EN | Sublime HQ Pty Ltd | Ficheiros de Texto | English Language Translation File | Notepad++ | Don Ho |
| .EPP | Talasoft | Ficheiros de Texto | TalaPhoto Project | TalaPhoto | Talasoft |
| .ERR | Microsoft Corporation | Ficheiros de Texto | Error Log File | Microsoft Notepad | Microsoft Corporation |
| .ES | Interscape | Ficheiros de Texto | ECHOSPEECH File | ECHOSPEECH | Interscape |
| .ES3 | Microsec Software Engineering & Consulting Plc. | Ficheiros de Texto | E-Szigno Signed Document | e-Szigno | Microsec Software Engineering & Consulting Plc. |
| .ESD | Microsoft Corporation | Ficheiros de Texto | Windows Electronic Software Download File | Microsoft Windows | Microsoft Corporation |
| .ESS | Bethesda Softworks | Ficheiros de Texto | The Elder Scrolls Saved Game | Skyrim VR | Bethesda Softworks |
| .ETF | NetScape | Ficheiros de Texto | Enriched Text Format E-mail Message | GNU Emacs | GNU Project |
| .ETS | Enthuware | Ficheiros de Texto | Enthuware Test Studio Document | Enthuware Test Studio | Enthuware |
| .ETX | Open Source | Ficheiros de Texto | TeX Font Encoding File | MiKTeX | Christian Schenk |
| .EUC | Unknown Developer | Ficheiros de Texto | Extended Unix Code File | EUC-JP decoder | Unknown Developer |
| .EXC | Lionhead Studios | Ficheiros de Texto | Black & White Zone File | Lionhead Studios Black and White | Lionhead Studios |
| .EZ | Open Source | Ficheiros de Texto | EZ Word Document | Andrew User Interface System | Open Source |
| .EZM | E-Press Corporation | Ficheiros de Texto | Text File Mail Data | EasyOffice | E-Press Corporation |
| .FAD | Microsoft Corporation | Ficheiros de Texto | Office File Attribute Database File | Microsoft Office | Microsoft Corporation |
| .FBL | International TechneGroup Incorporated | Ficheiros de Texto | CADfix Command Level Log File | CADfix | International TechneGroup Incorporated |
| .FCF | Final Draft | Ficheiros de Texto | Final Draft Converter File | Final Draft | Final Draft |
| .FCT | Salty Brine | Ficheiros de Texto | FolderClone Task List | Salty Brine FolderClone | Salty Brine |
| .FD | Data Access Worldwide | Ficheiros de Texto | DataFlex Data File | DataFlex | Data Access Worldwide |
| .FDF | Adobe Systems Incorporated | Ficheiros de Texto | Acrobat Forms Data Format | Adobe Acrobat DC | Adobe Systems Incorporated |
| .FDR | Final Draft | Ficheiros de Texto | Final Draft Document | Final Draft | Final Draft |
| .FDS | Adobe Systems Incorporated | Ficheiros de Texto | JetForm FormFlow Data File | JetForm FormFlow | Adobe Systems Incorporated |
| .FDT | Final Draft | Ficheiros de Texto | Final Draft 5-7 Template | Final Draft | Final Draft |
| .FDW | Nelfo | Ficheiros de Texto | FEBDOK Document File | FEBDOK | Nelfo |
| .FDX | Final Draft | Ficheiros de Texto | Final Draft Document | Final Draft | Final Draft |
| .FEE | Kalahari Software LLC | Ficheiros de Texto | Precision Fees Fee Schedule | Precision Fees | Kalahari Software LLC |
| .FFP | Open Source | Ficheiros de Texto | FLAC Fingerprint Data | Notepad++ | Don Ho |
| .FFT | Adobe Systems Incorporated | Ficheiros de Texto | Adobe Audition Noise Print File | Adobe Audition | Adobe Systems Incorporated |
| .FGS | Chen Lujie | Ficheiros de Texto | Fig Figure Settings File | Fig | Chen Lujie |
| .FIN | Interscape | Ficheiros de Texto | Sapir Torah Text | Sapir Torah | Interscape |
| .FIRE | CoffeeCup | Ficheiros de Texto | FireStarter Project File | CoffeeCup FireStarter | CoffeeCup |
| .FLR | Igor Kogan | Ficheiros de Texto | Flare Decompiled ActionScript File | Microsoft Notepad | Microsoft Corporation |
| .FORM | Oracle Corporation | Ficheiros de Texto | NetBeans Java GUI Designer Form | NetBeans | Open Source |
| .FPC | Microsoft Corporation | Ficheiros de Texto | FoxPro Catalog Memo | Microsoft Visual FoxPro | Microsoft Corporation |
| .FR | Sublime HQ Pty Ltd | Ficheiros de Texto | French Language Translation | Notepad++ | Don Ho |
| .FRT | Microsoft Corporation | Ficheiros de Texto | FoxPro Report Memo | Microsoft Visual FoxPro | Microsoft Corporation |
| .FSC | ProFantasy Software Ltd | Ficheiros de Texto | Campaign Cartographer File | Campaign Cartographer 3 | ProFantasy Software Ltd |
| .FSS | Basta Computing | Ficheiros de Texto | Splitty Data Split File | Basta Computing Splitty | Basta Computing |
| .FULL | Red Hat | Ficheiros de Texto | Cygwin Variable Log | Cygwin | Open Source |
| .FWD | Ipswitch, Inc. | Ficheiros de Texto | IMail Server Forwarded Mail Message | Ipswitch IMail Server | Ipswitch, Inc. |
| .FX | Microsoft Corporation | Ficheiros de Texto | Direct3D Effects File | Microsoft Visual Studio | Microsoft Corporation |
| .FX2 | Corel | Ficheiros de Texto | Corel WordPerfect Office Template File | Corel WordPerfect | Corel |
| .GBF | Yuku | Ficheiros de Texto | General Bible Format | Quick Bible | Yuku |
| .GDC | Iconics, Inc. | Ficheiros de Texto | Iconics GraphWorx32 Document | GraphWorX32 | Iconics, Inc. |
| .GER | Open Source | Ficheiros de Texto | German Text/html Info | Notepad++ | Don Ho |
| .GGG | Sharon Dugdale and David Kibbey | Ficheiros de Texto | Green Globs & Graphing Equations Records | Green Globs & Graphing Equations | Sharon Dugdale and David Kibbey |
| .GMD | YoYo Games | Ficheiros de Texto | Game Maker Program Code | GameMaker Studio | YoYo Games |
| .GMP | Blue Marble Geographics | Ficheiros de Texto | Global Mapper Package File | Global Mapper | Blue Marble Geographics |
| .GMX | YoYo Games | Ficheiros de Texto | GameMaker File | GameMaker Studio | YoYo Games |
| .GNU | Sublime HQ Pty Ltd | Ficheiros de Texto | GNU Licence Information | Sublime Text | Sublime HQ Pty Ltd |
| .GPD | Microsoft Corporation | Ficheiros de Texto | Generic Printer Description File | Microsoft Windows | Microsoft Corporation |
| .GPL | Open Source | Ficheiros de Texto | GNU Public License Text File | Microsoft Notepad | Microsoft Corporation |
| .GPN | Matt Herron | Ficheiros de Texto | GlidePlan Map Document | GlidePlan | Matt Herron |
| .GSD | PROFIBUS & PROFINET International | Ficheiros de Texto | General Station Description File | Microsoft Notepad | Microsoft Corporation |
| .GUIDE | Unknown Developer | Ficheiros de Texto | AmigaGuide Hypertext Document | Amiga Forever | Cloanto Corporation |
| .GUL | Samsung Electronics | Ficheiros de Texto | JungUm Global Document | JungUm Global | Samsung Electronics |
| .GV | AT&T Labs | Ficheiros de Texto | Graphviz DOT File | Graphviz | AT&T Labs |
| .GWB | Open Source | Ficheiros de Texto | Interwrite Presentation File | InterWrite Reader | Open Source |
| .GX | Saltire Software | Ficheiros de Texto | Geometry Expressions Document | Geometry Expressions | Saltire Software |
| .HBK | Mathsoft | Ficheiros de Texto | Mathcad Handbook File | Mathcad | PTC |
| .HCR | Broderbund | Ficheiros de Texto | Half-Fold Card File | CreataCard | American Greetings |
| .HDT | Adobe Systems Incorporated | Ficheiros de Texto | Photoshop HDR Toning Preset File | Adobe Photoshop CC | Adobe Systems Incorporated |
| .HLM | Adobe Systems Incorporated | Ficheiros de Texto | Winhelp Vbhilfe File | Adobe Authorware | Adobe Systems Incorporated |
| .HLX | Advanced Micro Devices, Inc. | Ficheiros de Texto | ATI Radeon Video Driver Support File | ATI Catalyst | Advanced Micro Devices, Inc. |
| .HM2 | EC Software | Ficheiros de Texto | Help And Manual 2 Project | Help & Manual | EC Software |
| .HMW | Tandy | Ficheiros de Texto | Homeword For DeskMate Document | Homeword for DeskMate | Tandy |
| .HNC | Interscape | Ficheiros de Texto | NoteCenter Note | NoteCenter | Interscape |
| .HOT | Electronic Arts | Ficheiros de Texto | The Sims Audio File | Electronic Arts SimCity 4 | Electronic Arts |
| .HPW | Hewlett-Packard | Ficheiros de Texto | Hewlett-Packard Word Document File | Corel WordPerfect | Corel |
| .HRX | Herolab | Ficheiros de Texto | Herolab E.A.S.Y Document | Herolab E.A.S.Y | Herolab |
| .HS | Open Source | Ficheiros de Texto | Haskell Script | MacroMates TextMate | MacroMates |
| .HTD | ResearchWare Inc. | Ficheiros de Texto | HyperTRANSCRIBE Document | HyperTRANSCRIBE | ResearchWare Inc. |
| .HVC | Sublime HQ Pty Ltd | Ficheiros de Texto | ASCII Text | Microsoft Notepad | Microsoft Corporation |
| .HWP | Hancom, Inc. | Ficheiros de Texto | Hanword Document | NeoOffice | Planamesa Software Inc. |
| .HWT | Huawei | Ficheiros de Texto | Huawei Emotion UI Theme | EMUI | Huawei |
| .HZ | Unknown Developer | Ficheiros de Texto | Chinese (Hanzi) Text | Unknown Software | Unknown Developer |
| .IGV | Broad Institute | Ficheiros de Texto | Integrative Genomics Viewer Data | Integrative Genomics Viewer | Broad Institute |
| .ILL | Unknown Developer | Ficheiros de Texto | Illust Logic Puzzle File | Unknown Software | Unknown Developer |
| .IRB | Yukihiro “Matz” Matsumoto | Ficheiros de Texto | Interactive Ruby Script | Ruby | Yukihiro “Matz” Matsumoto |
| .ISR | Open Source | Ficheiros de Texto | GoMoku Game File | Gomoku | Open Source |
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