| .73K | Texas Instruments, Inc. | File eseguibili | TI-73 Application | Tl-73 | Texas Instruments, Inc. |
| .A6P | Adobe Systems Incorporated | File eseguibili | Authorware 6 Program | Adobe Authorware | Adobe Systems Incorporated |
| .AC | GNU Operating System | File eseguibili | Autoconf Script | GNU Autoconf | GNU Operating System |
| .ACC | FKJ Software | File eseguibili | Graphics Accounts Data File | Graphic Accounts | FKJ Software |
| .ACTION | Apple | File eseguibili | Automator Action | Apple Automator | Apple |
| .AHK | Open Source | File eseguibili | AutoHotkey Script | AutoHotkey | Open Source |
| .AIF | Apple | File eseguibili | Audio Interchange File Format | Microsoft Windows Media Player | Microsoft Corporation |
| .AIR | Adobe Systems Incorporated | File eseguibili | Adobe AIR Installation Package | Adobe Animate CC 2017 | Adobe Systems Incorporated |
| .APP | Nokia | File eseguibili | Symbian OS Application | Symbian OS | Nokia |
| .ASB | Planit Solutions, Inc. | File eseguibili | Alphacam Stone VB Macro File | Planit Alphacam | Planit Solutions, Inc. |
| .AZW2 | Amazon | File eseguibili | Amazon Kindle Program | Amazon Kindle | Amazon |
| .BAT | Microsoft Corporation | File eseguibili | DOS Batch File | Notepad++ | Don Ho |
| .BEAM | Ericsson Computer Science Laboratory | File eseguibili | Compiled Erlang File | Erlang | Ericsson Computer Science Laboratory |
| .BHTML | Parameshwar Babu | File eseguibili | BabuHTML Embedded Software File | BabuHTML | Parameshwar Babu |
| .BIN | Unknown Developer | File eseguibili | Binary Disk Image File | IsoBuster | Smart Projects |
| .BOI | TNHteam | File eseguibili | Botje Bot-File | Botje | TNHteam |
| .BTM | Microsoft Corporation | File eseguibili | BizTalk Map File | BizTalk Server | Microsoft Corporation |
| .CAC | dBase, LLC | File eseguibili | dBASE IV Executable Data | dBase | dBase, LLC |
| .CEL | Affymetrix | File eseguibili | Affymetrix Probe Results File | The MathWorks MATLAB | MathWorks |
| .CELX | Open Source | File eseguibili | Celestia Script File | Microsoft Notepad | Microsoft Corporation |
| .CGI | Unknown Developer | File eseguibili | Common Gateway Interface Script | Microsoft Notepad | Microsoft Corporation |
| .CLX | IBM | File eseguibili | Rational XDE | Rational XDE | IBM |
| .CMD | Microsoft Corporation | File eseguibili | Windows Command File | Microsoft Notepad | Microsoft Corporation |
| .COF | Microchip Technology Inc. | File eseguibili | MPLAB COFF File | MPLAB IDE | Microchip Technology Inc. |
| .COFFEE | Sublime HQ Pty Ltd | File eseguibili | CoffeeScript Script | Sublime Text | Sublime HQ Pty Ltd |
| .COM | Microsoft Corporation | File eseguibili | DOS Command File | Microsoft Windows | Microsoft Corporation |
| .CSH | Adobe Systems Incorporated | File eseguibili | Photoshop Custom Shapes File | Adobe Photoshop Elements | Adobe Systems Incorporated |
| .CYW | Unknown Developer | File eseguibili | Rbot.CYW Worm File | Should Not Be Opened Manually | Unknown Developer |
| .DEK | Wizards of the Coast | File eseguibili | Magic: The Gathering Deck File | Magic | Interscape |
| .DLD | Campbell Scientific | File eseguibili | EdLog Compiled Program | LoggerNet | Campbell Scientific |
| .DMC | nModal Solutions Inc. | File eseguibili | Datamartist Data Canvas File | nModal Solutions Datamartist | nModal Solutions Inc. |
| .DXL | IBM | File eseguibili | Domino XML Language File | Microsoft Notepad | Microsoft Corporation |
| .DZEP | CyberLink | File eseguibili | PowerDirector File | PowerDirector | CyberLink |
| .EAR | Oracle Corporation | File eseguibili | Java Enterprise Archive File | WebSphere Application Server | IBM |
| .EBS | Psychology Software Tools, Inc. | File eseguibili | E-Run Version 1 Script File | E-Prime | Psychology Software Tools, Inc. |
| .ECF | Microsoft Corporation | File eseguibili | Outlook Add-in | Microsoft Outlook | Microsoft Corporation |
| .ELF | Nintendo | File eseguibili | Nintendo Wii Game File | Dolphin (emulator) | Dolphin Emulator Project |
| .EPK | LG Electronics | File eseguibili | LG Firmware Package | epk2extract | openlgtv |
| .ESH | Microsoft Corporation | File eseguibili | Extended Shell Batch File | MS-DOS | Microsoft Corporation |
| .EX1 | Igor Pavlov | File eseguibili | Renamed EXE File | 7-Zip | Igor Pavlov |
| .EXA | Aquila Software | File eseguibili | Examine32 Saved Search Paramaters File | Examine32 | Aquila Software |
| .EXE | Microsoft Corporation | File eseguibili | Windows Executable File | 7-Zip | Igor Pavlov |
| .EXEC | Open Source | File eseguibili | Unix Executable File | FreeBSD | The FreeBSD Community |
| .EZS | EZ-R Stats | File eseguibili | EZ-R Stats Batch Script | EZ-R Stats for Windows | EZ-R Stats |
| .EZT | EZTitles Development Studio | File eseguibili | EZTitles Subtitles File | EZTitles | EZTitles Development Studio |
| .E_E | Igor Pavlov | File eseguibili | Renamed EXE File | 7-Zip | Igor Pavlov |
| .FAS | Autodesk, Inc. | File eseguibili | Compiled Fast-Load AutoLISP File | Autodesk AutoCAD | Autodesk, Inc. |
| .FKY | Microsoft Corporation | File eseguibili | FoxPro Macro | Microsoft Visual FoxPro | Microsoft Corporation |
| .FMX | FileMaker Inc. | File eseguibili | FileMaker Plug-in | FileMaker Pro | FileMaker Inc. |
| .FPI | The Game Creators | File eseguibili | FPS Creator Intelligence Script | Dimenzo Text Editor | Dimenzo, Inc. |
| .FPX | Kodak | File eseguibili | FlashPix Bitmap Image File | Kodak EasyShare | Kodak |
| .FRS | Corel | File eseguibili | Corel WordPerfect Screen Font Resource File | Corel WordPerfect | Corel |
| .FXP | Microsoft Corporation | File eseguibili | FoxPro Compiled Program | Microsoft Visual FoxPro | Microsoft Corporation |
| .GADGET | Microsoft Corporation | File eseguibili | Windows Gadget | Microsoft Windows | Microsoft Corporation |
| .HAM | Interplay Entertainment | File eseguibili | Descent 2 Resource File | Interplay Descent 2 | Interplay Entertainment |
| .HMS | Advanced Network Software | File eseguibili | HostMonitor Script File | HostMonitor | Advanced Network Software |
| .HPF | IBM | File eseguibili | High Performance Fortran File | Microsoft Notepad | Microsoft Corporation |
| .HTA | Microsoft Corporation | File eseguibili | HTML Application | Internet Explorer | Microsoft Corporation |
| .HZX | Rowley Associates Ltd | File eseguibili | CrossWorks Executable File | CrossWorks for ARM | Rowley Associates Ltd |
| .ICD | Macrovision Corporation | File eseguibili | SafeDisc Encrypted Program | SafeDisc | Macrovision Corporation |
| .IIM | Ipswitch, Inc. | File eseguibili | iMacro Macro File | Mozilla Firefox | Mozilla |
| .IPA | Apple | File eseguibili | Apple iOS Application | Apple iTunes | Apple |
| .IPI | Microsoft Corporation | File eseguibili | Microsoft Windows Installer Data | Microsoft Windows | Microsoft Corporation |
| .IRX | Martin Stanek | File eseguibili | Brewer Irradiation File | UVBrewer | Interscape |
| .ISU | Flexera Software | File eseguibili | InstallShield Uninstaller Script | InstallShield | Flexera Software |
| .ITA | Unknown Developer | File eseguibili | IconTweaker Theme Archive | IconTweaker | Unknown Developer |
| .JSE | Microsoft Corporation | File eseguibili | JScript Encoded File | Microsoft Visual Studio | Microsoft Corporation |
| .JSX | Adobe Systems Incorporated | File eseguibili | ExtendScript Script File | Adobe After Effects | Adobe Systems Incorporated |
| .KIX | Ruud Van Velsen | File eseguibili | KiXtart Script File | Notepad++ | Don Ho |
| .KMD | Open Source | File eseguibili | ABSTAT For Windows Batch File | ABstat | Open Source |
| .KSH | AT&T Labs | File eseguibili | Unix Korn Shell Script | AbiWord | Open Source |
| .KX | Ruud Van Velsen | File eseguibili | KiXtart Tokenized Script | KixTart | Ruud Van Velsen |
| .LE | Microsoft Corporation | File eseguibili | DOS/4GW PM 32X DOS Extender Executable Image | MS-DOS | Microsoft Corporation |
| .LKU | STMicroelectronics | File eseguibili | ST Microelectronics Linked Unit Data | Unknown Software | Unknown Developer |
| .LO | BroadVision | File eseguibili | Interleaf Compiled Lisp File | QuickSilver | Micrografx |
| .LS | NewTek | File eseguibili | LightWave LScript File | LightWave 3D | NewTek |
| .M3G | Nokia | File eseguibili | Mobile 3D Graphics Program | Nokia Mobile Phone Software | Nokia |
| .MAM | Microsoft Corporation | File eseguibili | Microsoft Access Macro | Microsoft Access | Microsoft Corporation |
| .MCR | Mojang | File eseguibili | Minecraft Region File | Minecraft | Mojang |
| .MEL | Autodesk, Inc. | File eseguibili | Maya Embedded Language File | Autodesk Maya | Autodesk, Inc. |
| .MEM | Microsoft Corporation | File eseguibili | FoxPro Variable File | Microsoft Visual FoxPro | Microsoft Corporation |
| .MEX | MathWorks | File eseguibili | MATLAB Dynamically Linked Subroutine File | The MathWorks MATLAB | MathWorks |
| .MIO | Open Source | File eseguibili | MioEngine Application File | MioFactory | Open Source |
| .MLX | MathWorks | File eseguibili | MATLAB Live Script | The MathWorks MATLAB | MathWorks |
| .MM | Kodak | File eseguibili | Kodak EasyShare Thumbnail Cache File | Kodak EasyShare | Kodak |
| .MMX | Interscape | File eseguibili | Command And Conquer Game Data | Command and Conquer | Interscape |
| .MPX | Microsoft Corporation | File eseguibili | FoxPro Compiled Menu Program | Microsoft Visual FoxPro | Microsoft Corporation |
| .MRC | mIRC Co. Ltd | File eseguibili | mIRC Script File | mIRC | mIRC Co. Ltd |
| .MS | Next Limit Technologies | File eseguibili | Maxwell Script | Maxwell Render | Next Limit Technologies |
| .MSL | Microsoft Corporation | File eseguibili | Mapping Specification Language File | Microsoft Notepad | Microsoft Corporation |
| .MXE | Insight Software Solutions | File eseguibili | Macro Express Playable Macro | Macro Express | Insight Software Solutions |
| .N | Nicolas Cannasse | File eseguibili | Neko Bytecode File | Neko | Nicolas Cannasse |
| .NDR | Nikon | File eseguibili | Nikon Capture Image Dust Off File | Nikon Capture NX | Nikon |
| .ORE | Crait Corp. | File eseguibili | Ore Executable File | Ore Runtime Environment | Jonathan Holmes |
| .OSX | Apple | File eseguibili | PowerPC Executable File | macOS | Apple |
| .OTM | Microsoft Corporation | File eseguibili | Outlook Macro File | Microsoft Word | Microsoft Corporation |
| .OUT | Open Source | File eseguibili | Compiled Executable File | Linux | Open Source |
| .PAF | FamilySearch | File eseguibili | Personal Ancestral File | Personal Ancestral File | FamilySearch |
| .PE | Microsoft Corporation | File eseguibili | Portable Executable File | Microsoft Windows | Microsoft Corporation |
| .PEX | Schlumberger Limited | File eseguibili | Merak Peep Data File | Merak Peep | Schlumberger Limited |
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