| .CDF | Wolfram Research | File con layout di pagina | Computable Document Format File | Wolfram Research CDF Player | Wolfram Research |
| .FITS | Open Source | File con immagini raster | Flexible Image Transport System File | Wolfram Research Mathematica | Wolfram Research |
| .M | MathWorks | File sviluppatore | MATLAB Source Code File | Wolfram Research Mathematica | Wolfram Research |
| .MA | Autodesk, Inc. | File 3D | Maya Project File | Wolfram Research Mathematica | Wolfram Research |
| .MDB | Microsoft Corporation | File di database | Microsoft Access Database | Wolfram Research Mathematica | Wolfram Research |
| .MM | Kodak | File di dati | Kodak EasyShare Thumbnail Cache File | Wolfram Research Mathematica | Wolfram Research |
| .MX | Wolfram Research | File di dati | Mathematica Serialized Package File | Wolfram Research Mathematica | Wolfram Research |
| .NB | Wolfram Research | File con fogli di calcolo | Mathematica Notebook | Wolfram Research Mathematica | Wolfram Research |
| .NBP | Wolfram Research | File di dati | Mathematica Player Notebook File | Wolfram Research Mathematica | Wolfram Research |
| .PIXAR | Pixar | File con immagini raster | Pixar Image File | Wolfram Research Mathematica | Wolfram Research |
| .PLY | MakeMusic, Inc. | File audio | Finale Playback File | Wolfram Research Mathematica | Wolfram Research |
| .PNM | XnSoft | File con immagini raster | Portable Any Map Image | Wolfram Research Mathematica | Wolfram Research |
| .PXR | Pixar | File con immagini raster | Pixar Image File | Wolfram Research Mathematica | Wolfram Research |
| .TGF | Unknown Developer | File di dati | Trivial Graph Format File | Wolfram Research Mathematica | Wolfram Research |
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