| .D2V | Interscape | Video Files | DVD2AVI File | VirtualDub | Open Source |
| .DA2 | Microsoft Corporation | Video Files | Windows Dancer File | Windows Media Center | Microsoft Corporation |
| .DAPROJ | DivX, LLC. | Video Files | DivX Author Project File | DivX | DivX, LLC. |
| .DAT | Unknown Developer | Video Files | Game Data | Dragon UnPACKer | Open Source |
| .DAV | DVR365 | Video Files | DVR365 Video File | Amcrest Smart Player | Amcrest Technologies |
| .DB2 | Samsung Electronics | Video Files | Samsung CCTV Video Information File | Samsung SmartViewer | Samsung Electronics |
| .DCE | LYTX | Video Files | DriveCam Video File | DriveCam Event Player | LYTX |
| .DGW | Digi-Watcher | Video Files | Digi-Watcher Video Data | Digi-Watcher | Digi-Watcher |
| .DIF | Microsoft Corporation | Video Files | Data Interchange Format | Microsoft Excel | Microsoft Corporation |
| .DIR | Adobe Systems Incorporated | Video Files | Adobe Director Movie | Adobe Director | Adobe Systems Incorporated |
| .DIV | Robert Hijmans | Video Files | DIVA-GIS Project File | DIVA-GIS | Robert Hijmans |
| .DIVX | DivX, LLC. | Video Files | DivX-Encoded Movie File | CyberLink PowerDVD | CyberLink |
| .DLX | DIAL | Video Files | DIALux Document | DIAL DIALux | DIAL |
| .DMB | BYOND | Video Files | BYOND Game Executable | BYOND | BYOND |
| .DMSD | Sonic Solutions | Video Files | Roxio MyDVD Project | Roxio Creator NXT Pro 6 | Roxio |
| .DMV | Adobe Systems Incorporated | Video Files | Adobe Acrobat Catalog Data | Adobe Acrobat DC | Adobe Systems Incorporated |
| .DMX | Valve | Video Files | Source Filmmaker Project File | Source Filmmaker | Valve |
| .DNC | Microsoft Corporation | Video Files | Windows Dancer File | Windows Media Center | Microsoft Corporation |
| .DPA | Serif | Video Files | DrawPlus Animation File | Serif DrawPlus | Serif |
| .DPD | David Pilling | Video Files | Ovation Pro File | Ovation Pro Reader | David Pilling |
| .DPG | Open Source | Video Files | Nintendo DS Movie File | MoonShell | Open Source |
| .DRC | Open Source | Video Files | Open Mobile Alliance DRM Rights Object | Microsoft Notepad | Microsoft Corporation |
| .DREAM | Stardock Corporation | Video Files | Dream Animated Wallpaper File | DreamMaker | Stardock Corporation |
| .DRT | Micrografx | Video Files | Micrografix Windows Draw Template File | Micrografix Windows Draw | Micrografx |
| .DSL | ABBYY | Video Files | Lingvo Dictionary Data File | ABBYY Lingvo Dictionary | ABBYY |
| .DSY | Lead System (M) Sdn. Bhd. | Video Files | Besta Video File | Besta Electronic Dictionaries | Lead System (M) Sdn. Bhd. |
| .DTCP-IP | Microsoft Corporation | Video Files | Microsoft Windows Movie Maker Video | Microsoft Windows Live Movie Maker | Microsoft Corporation |
| .DTV | Interscape | Video Files | DVD2AVI Mpeg2 File | DVD2AVI | Interscape |
| .DV | Roxio | Video Files | Digital Video File | Microsoft Windows Live Movie Maker | Microsoft Corporation |
| .DV4 | Bosch Security Systems | Video Files | Bosch Security Systems CCTV Video File | Bosch Security Systems Archive Player | Bosch Security Systems |
| .DVDRIP | Unknown Developer | Video Files | DVD Disk Image | Unknown Software | Unknown Developer |
| .DVM | Open Source | Video Files | DVM Movie File Format | DVM development kit | Open Source |
| .DVR | Microsoft Corporation | Video Files | Microsoft Recorded TV Show | VLC Media Player | VideoLAN |
| .DVR-MS | Microsoft Corporation | Video Files | Microsoft Digital Video Recording | CyberLink PowerDVD | CyberLink |
| .DVT | inData | Video Files | DepoView Digital Video Transcript | DepoView | inData |
| .DVX | DivX, LLC. | Video Files | DivX Video File | CyberLink PowerDVD | CyberLink |
| .DXR | Adobe Systems Incorporated | Video Files | Protected Macromedia Director Movie | Adobe Director | Adobe Systems Incorporated |
| .DZP | CyberLink | Video Files | DirectorZone Particle Effect File | CyberLink PowerDirector 15 Ultra | CyberLink |
| .DZT | CyberLink | Video Files | DirectorZone Title File | CyberLink PowerDirector 15 Ultra | CyberLink |
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