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| Extension | File Type Developer | File Category | File Type Description | Primary Software | Primary Software Developer |
|---|---|---|---|---|---|
| .EDN | Xilinx, Inc. | Text Files | EDIF Implementation Netlist File | Xilinx ISE WebPACK | Xilinx, Inc. |
| .EDOC | EUSO | Text Files | Electronically Certified Document | EDOC Java Libraries | EUSO |
| .EGT | EagleGet | Text Files | EagleGet Temporary File | EagleGet | EagleGet |
| .EIM | EIAS3D | Text Files | Electric Image Model | Electric Image Animation System (EIAS) | EIAS3D |
| .EIO | Yozosoft | Text Files | Yozo Office File | Yozosoft Yozo Office | Yozosoft |
| .EIT | Yozosoft | Text Files | Yozo Office Template File | Yozosoft Yozo Office | Yozosoft |
| .EMD | FMJ-Software | Text Files | ABT Extended Module File | Awave Studio | FMJ-Software |
| .EMF | Microsoft Corporation | Text Files | Enhanced Windows Metafile | Apache OpenOffice | Apache Software Foundation |
| .EMLX | Apple | Text Files | Apple Mail Message | Notepad++ | Don Ho |
| .EN | Sublime HQ Pty Ltd | Text Files | English Language Translation File | Notepad++ | Don Ho |
| .EPP | Talasoft | Text Files | TalaPhoto Project | TalaPhoto | Talasoft |
| .ERR | Microsoft Corporation | Text Files | Error Log File | Microsoft Notepad | Microsoft Corporation |
| .ES | Interscape | Text Files | ECHOSPEECH File | ECHOSPEECH | Interscape |
| .ES3 | Microsec Software Engineering & Consulting Plc. | Text Files | E-Szigno Signed Document | e-Szigno | Microsec Software Engineering & Consulting Plc. |
| .ESD | Microsoft Corporation | Text Files | Windows Electronic Software Download File | Microsoft Windows | Microsoft Corporation |
| .ESS | Bethesda Softworks | Text Files | The Elder Scrolls Saved Game | Skyrim VR | Bethesda Softworks |
| .ETF | NetScape | Text Files | Enriched Text Format E-mail Message | GNU Emacs | GNU Project |
| .ETS | Enthuware | Text Files | Enthuware Test Studio Document | Enthuware Test Studio | Enthuware |
| .ETX | Open Source | Text Files | TeX Font Encoding File | MiKTeX | Christian Schenk |
| .EUC | Unknown Developer | Text Files | Extended Unix Code File | EUC-JP decoder | Unknown Developer |
| .EXC | Lionhead Studios | Text Files | Black & White Zone File | Lionhead Studios Black and White | Lionhead Studios |
| .EZ | Open Source | Text Files | EZ Word Document | Andrew User Interface System | Open Source |
| .EZM | E-Press Corporation | Text Files | Text File Mail Data | EasyOffice | E-Press Corporation |
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