| .MBI | MagicISO Inc. | Disk billedfiler | Multi-Bootable Information File | MagicISO | MagicISO Inc. |
| .MD0 | Alcohol Soft | Disk billedfiler | Alcohol Disk Image Segment 1 | Alcohol 120% | Alcohol Soft |
| .MD1 | Alcohol Soft | Disk billedfiler | Alcohol Disk Image Segment 2 | Alcohol 120% | Alcohol Soft |
| .MD2 | Alcohol Soft | Disk billedfiler | Alcohol Disk Image Segment 2 | Alcohol 120% | Alcohol Soft |
| .MDF | Alcohol Soft | Disk billedfiler | Alcohol 120% Disk Image File Format | IsoBuster | Smart Projects |
| .MDO | Alcohol Soft | Disk billedfiler | Alcohol 120% Split Image File | Alcohol 120% | Alcohol Soft |
| .MDS | SmartBear | Disk billedfiler | TestComplete Project File | TestComplete | SmartBear |
| .MDV | Open Source | Disk billedfiler | QLAY MDV Image | QLAY | Open Source |
| .MDX | Disc Soft Ltd. | Disk billedfiler | Extended Media Descriptor File | DAEMON Tools | Disc Soft Ltd. |
| .MGI | RedFox | Disk billedfiler | CloneCD Disk Image | CloneCD | RedFox |
| .MLC | Microsoft Corporation | Disk billedfiler | Microsoft Language Interface Pack | Microsoft Windows | Microsoft Corporation |
| .MRIMG | Paramount Software UK Ltd | Disk billedfiler | Macrium Reflect Disk Image | Macrium Reflect | Paramount Software UK Ltd |
| .NCD | Nero AG | Disk billedfiler | Nero CoverDesigner File | Nero CoverDesigner | Nero AG |
| .NDZ | Open Source | Disk billedfiler | Emulab Frisbee Disk Image | Emulab | Open Source |
| .NFI | Dream Multimedia | Disk billedfiler | Dreambox Disc Image | FlashWizard PRO | DreamLogic Software |
| .NMD | Nero AG | Disk billedfiler | Nero MiniDVD Compilation Data | Nero Burning ROM | Nero AG |
| .NRG | Nero AG | Disk billedfiler | Nero CD/DVD Image File | IsoBuster | Smart Projects |
| .NRI | Nero AG | Disk billedfiler | Nero ISO CD Compilation File | Nero Burning ROM | Nero AG |
| .NRV | Nero AG | Disk billedfiler | Nero Video-CD Compilation File | Nero 2017 | Nero AG |
| .NRW | Nikon | Disk billedfiler | Nikon Raw Image File | MacPhun ColorStrokes | Macphun |
| .OMG | O&O Software | Disk billedfiler | O&O Image File | O&O DiskImage | O&O Software |
| .P01 | HERE | Disk billedfiler | HERE Maps For Android Map Data Package | HERE Maps | HERE |
| .P2G | CyberLink | Disk billedfiler | Power2Go Project File | Power2Go | CyberLink |
| .PARTIMG | Unknown Developer | Disk billedfiler | Partimage File | Partition Image | Open Source |
| .PDI | Pinnacle Systems Inc. | Disk billedfiler | InstantCopy Disc Image | Lightning UK! ImgBurn | Lightning UK! |
| .PGD | Symantec Corporation | Disk billedfiler | PGP Disk Image | PGP Desktop | Symantec Corporation |
| .PGX | Hopedot Electronics | Disk billedfiler | Hopedot VOS Data File | Hopedot VOS | Hopedot Electronics |
| .PMF | ESRI | Disk billedfiler | ESRI Published Map File | ESRI ArcGIS for Desktop | ESRI (Environmental Systems Research Institute) |
| .PO | Sublime HQ Pty Ltd | Disk billedfiler | Portable Object | Apache OpenOffice | Apache Software Foundation |
| .PQI | Symantec Corporation | Disk billedfiler | PowerQuest Drive Image | Symantec Ghost Solution Suite | Symantec Corporation |
| .PVM | Parallels | Disk billedfiler | Parallels Virtual Machine | VMware Fusion | VMware |
| .PXI | Plextor | Disk billedfiler | PlexTools Disk Image File | IsoBuster | Smart Projects |
| .QCOW2 | Open Source | Disk billedfiler | QEMU Copy On Write Version 2 Disk Image | Quick Emulator (QEMU) | Open Source |
| .RATDVD | RatDVD | Disk billedfiler | RatDVD Disk Image | Microsoft Windows Media Player | Microsoft Corporation |
| .RAW | Unknown Developer | Disk billedfiler | Raw Image Data File | MacPhun ColorStrokes | Macphun |
| .RCL | Sonic Solutions | Disk billedfiler | Easy CD And DVD Creator 6 Project File | Roxio Creator NXT Pro 5 | Roxio |
| .RDF | Unknown Developer | Disk billedfiler | Resource Description Framework File | Mozilla Firefox | Mozilla |
| .SCO | MR Software | Disk billedfiler | OMSI Scenery Object Configuration File | OMSI | MR Software |
| .SDI | Intuit, Inc. | Disk billedfiler | QuickBooks Data File | Intuit QuickBooks Pro | Intuit, Inc. |
| .SEV | Open Source | Disk billedfiler | SevenUp Picture | ZX-Paintbrush | Open Source |
| .SMI | Apple | Disk billedfiler | Self-Mounting Disk Image | ShrinkWrap | Aladdin Systems |
| .SUB | URUWORKS | Disk billedfiler | Subtitle File | CyberLink PowerDVD | CyberLink |
| .SWM | Microsoft Corporation | Disk billedfiler | Split Windows Imaging Format File | Microsoft ImageX | Microsoft Corporation |
| .T64 | Commodore International | Disk billedfiler | Commodore 64 Tape Image File | Power64 | MacUpdate |
| .TAO | Smart Projects | Disk billedfiler | Track At Once CD/DVD Image | IsoBuster | Smart Projects |
| .TAP | Various Developers | Disk billedfiler | Commodore 64 Cassette Tape Image | Fuse | Open Source |
| .TBI | Electronic Arts | Disk billedfiler | FIFA 2001 Game Data | FIFA 2001 | EA Sports |
| .TC | TrueCrypt | Disk billedfiler | TrueCrypt Volume | TrueCrypt | TrueCrypt |
| .TD0 | Sydex | Disk billedfiler | Teledisk Archive | Teledisk | Sydex |
| .TDI | Toshiba Corporation | Disk billedfiler | Toshiba Disc Creator Image | Toshiba Disc Creator | Toshiba Corporation |
| .TIB | Acronis | Disk billedfiler | Acronis True Image File | VMware vCenter Converter | VMware |
| .TOAST | Roxio | Disk billedfiler | Toast Disc Image | Roxio Toast 15 | Roxio |
| .TOC | Sony | Disk billedfiler | Sony PlayStation Portable (PSP) Audio File | Exact Audio Copy for PSP Edition | Interscape |
| .TZX | Kromasoft | Disk billedfiler | Tanzzle Graphic Object File | Tanzzle Game | Kromasoft |
| .UBIFS | Various Developers | Disk billedfiler | Linux UBIFS Image | Linux | Open Source |
| .UDF | Open Source | Disk billedfiler | Universal Disk Format Image File | 7-Zip | Igor Pavlov |
| .UFS | iXsystems | Disk billedfiler | FreeBSD Unix File System File | iXsystems PC-BSD | iXsystems |
| .UIF | MagicISO Inc. | Disk billedfiler | Universal Image Format Disc Image | MagicISO | MagicISO Inc. |
| .VC4 | Microsoft Corporation | Disk billedfiler | Visual C++ 4 File | Notepad++ | Don Ho |
| .VCD | H+H Software GmbH | Disk billedfiler | Virtual CD | MPlayer | The MPlayer Team |
| .VCX | H+H Software GmbH | Disk billedfiler | Virtual Disc Definition File | H+H Software Virtual CD | H+H Software GmbH |
| .VDD | Phantombility, Inc | Disk billedfiler | Phantom Burner Virtual Disk Image | Phantom Burner | Phantombility, Inc |
| .VDI | Oracle Corporation | Disk billedfiler | VirtualBox Virtual Disk Image | Oracle VM VirtualBox | Oracle Corporation |
| .VFD | Microsoft Corporation | Disk billedfiler | Virtual Floppy Disk | Gilles Vollant WinImage | Gilles Vollant |
| .VHD | Microsoft Corporation | Disk billedfiler | VHDL Source File | Microsoft Notepad | Microsoft Corporation |
| .VHDX | Microsoft Corporation | Disk billedfiler | Windows 8 Virtual Hard Drive File | Microsoft Windows Server 2016 | Microsoft Corporation |
| .VMA | Proxmox Server Solutions | Disk billedfiler | Proxmox Virtual Machine Archive | Proxmox VE | Proxmox Server Solutions |
| .VMDK | VMware | Disk billedfiler | Virtual Machine Disk File | VMware Workstation | VMware |
| .VOL | Open Source | Disk billedfiler | Video Game Archive | Dragon UnPACKer | Open Source |
| .WB | Electronic Arts | Disk billedfiler | FIFA 2000 Game Data | FIFA 2000 | Electronic Arts |
| .WIL | Gilles Vollant | Disk billedfiler | WinImage Disk Image List | Gilles Vollant WinImage | Gilles Vollant |
| .WIM | Microsoft Corporation | Disk billedfiler | Windows Imaging Format File | 7-Zip | Igor Pavlov |
| .WLZ | Gilles Vollant | Disk billedfiler | WinImage Compressed Disk Image | Gilles Vollant WinImage | Gilles Vollant |
| .X64 | Commodore International | Disk billedfiler | Commodore 64 Disk Image | Power64 | MacUpdate |
| .XA | Electronic Arts | Disk billedfiler | The Sims Audio File | Electronic Arts SimCity 4 | Electronic Arts |
| .XDF | NASA | Disk billedfiler | Extended Disk Format Image | OS/2 | IBM |
| .XDI | Power Software Ltd | Disk billedfiler | WinArchiver Extended Disk Image File | WinArchiver Virtual Drive | Power Software Ltd |
| .XGS | Microsoft Corporation | Disk billedfiler | XACT Global Settings File | Microsoft XACT | Microsoft Corporation |
| .XMD | Bitdefender | Disk billedfiler | Bitdefender Plugin File | Bitdefender Total Security 2018 | Bitdefender |
| .XMF | Open Source | Disk billedfiler | Cal3D XML Mesh File | Cal3DViewer | Open Source |
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